Ketol-acid reductoisomerase 3D structures

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**[[5w3k]], [[6aqj]] – SaKARI + NADPH + Mg – ''Staphyloccocus aureus''<br />
**[[5w3k]], [[6aqj]] – SaKARI + NADPH + Mg – ''Staphyloccocus aureus''<br />
**[[6bul]], [[6c55]], [[6c5n]] – SaKARI + NADPH + Mg + hydroxyoxamate inhibitor<br />
**[[6bul]], [[6c55]], [[6c5n]] – SaKARI + NADPH + Mg + hydroxyoxamate inhibitor<br />
 +
**[[7ke2]], [[9b9p]], [[9bae]] – SaKARI + Mg + pyrimidine inhibitor<br />
 +
**[[7kh7]] – SaKARI + NADPH + Mg + pyrimidine inhibitor<br />
 +
**[[6vo2]] – SaKARI + NADPH + Mg + inhibitor<br />
**[[4kqx]] – SeKARI + NAD + Mg + hydroxyl-isopropyloxamate <br />
**[[4kqx]] – SeKARI + NAD + Mg + hydroxyl-isopropyloxamate <br />
-
**[[6jcw]], [[6kou]], [[6kpe]], [[6kpi]], [[6kpk]], [[6kq4]], [[6kq8]] – SsKARI + Mg – ''Saccharolobus solfataricus'' – Cryo EM<br />
+
**[[6jcv]], [[6jcw]], [[6kou]], [[6kpe]], [[6kpi]], [[6kpk]], [[6kq4]], [[6kq8]] – SsKARI + Mg – ''Saccharolobus solfataricus'' – Cryo EM<br />
 +
**[[6jd2]] – SsKARI + Mg <br />
**[[6kpa]], [[6kph]], [[6kpj]], [[6kqj]], [[6kqk]], [[6kqo]] – SsKARI + Mg + NAD – Cryo EM<br />
**[[6kpa]], [[6kph]], [[6kpj]], [[6kqj]], [[6kqk]], [[6kqo]] – SsKARI + Mg + NAD – Cryo EM<br />
 +
**[[6jcz]], [[6jd1]] – SsKARI + NADP + Mg + dicarboxylate derivative – Cryo EM<br />
**[[6jx2]] – KARI + NADPH + Mg – ''Corynebacterium glutamicum''<br />
**[[6jx2]] – KARI + NADPH + Mg – ''Corynebacterium glutamicum''<br />
**[[6l2k]], [[6l2r]], [[6l2s]], [[6l2z]] – SpKARI (mutant) – ''Streptococcus pneumoniae''<br />
**[[6l2k]], [[6l2r]], [[6l2s]], [[6l2z]] – SpKARI (mutant) – ''Streptococcus pneumoniae''<br />
**[[6l2i]] – SpKARI + NADPH + Mg <br />
**[[6l2i]] – SpKARI + NADPH + Mg <br />
-
**[[6vo2]] – SpKARI + NADPH + Mg + inhibitor<br />
+
**[[7pci]], [[7pcm]], [[7pcn]] – BtKARI + NADH + Mg + enoate derivative – ''Burkholderia thailandensis''<br />
 +
**[[7pcc]] – BtKARI + NADH + Mg <br />
 +
**[[7pco]], [[7pct]] – BtKARI (mutant) + NADH + Mg + enoate derivative <br />
 +
**[[7pcg]] – BtKARI + NADH + Mg + bicarboxylate derivative <br />
 +
**[[7pcl]] – BtKARI + NADH + Mg + ethanoate derivative <br />
 +
**[[7pce]] – BtKARI + ADP<br />
 +
**[[8ep7]] – KARI + NADP + Mg – ''Bacillus anthracis''<br />
 +
**[[8cy8]] – CjKARI – ''Campylobacter jejuni'' – Cryo EM<br />
 +
**[[7lat]] – CjKARI + Mg <br />
 +
**[[7rdu]], [[8upn]], [[8upp]] – CjKARI + NADP + Mg<br />
 +
**[[8sxd]] – CjKARI + NADP + nicotinamide + Mg<br />
 +
**[[8swm]] – CjKARI + acetolactate + Mg<br />
 +
**[[8upq]] – CjKARI + isovalerate + Mg<br />
 +
**[[7q03]] – MtKARI + NADP – ''Methanothermococcus thermolithotropicus''<br />
 +
**[[7q07]] – MtKARI + NADP + tartarate <br />
 +
**[[7toc]] – KARI + NADP + Mg – ''Candida auris''<br />
 +
**[[8pve]] – TtKARI – ''Thermus thermophilus''<br />
 +
**[[8pru]] – TtKARI + Mg <br />
 +
**[[8k32]] – KARI + NADH + Mg – ''Syntrophothermus lipocalidus''<br />
*KARI class II
*KARI class II
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**[[3fr7]] – rKARI + Mg - rice<br />
**[[3fr7]] – rKARI + Mg - rice<br />
**[[3fr8]] – rKARI + NADPH + Mg<br />
**[[3fr8]] – rKARI + NADPH + Mg<br />
 +
**[[9bag]] – rKARI + inhibitor + Mg<br />
**[[1yve]] – sKARI + NADPH + hydroxyl-isopropyloxamate - spinach<br />
**[[1yve]] – sKARI + NADPH + hydroxyl-isopropyloxamate - spinach<br />
**[[1qmg]] – sKARI + Mn + dihydroxy-valerianate + AMP-diphosphoribose<br />
**[[1qmg]] – sKARI + Mn + dihydroxy-valerianate + AMP-diphosphoribose<br />

Current revision

3D Structures of Ketol-acid reductoisomerase

Updated on 19-October-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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