This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Latrophilin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:38, 18 June 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 12: Line 12:
</StructureSection>
</StructureSection>
-
==3D structures of latropilin==
+
==3D structures of latrophilin==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Line 25: Line 25:
**[[5ftt]], [[5ftu]] – hLAT-3 + FLRT2 + netrin receptor - human<br />
**[[5ftt]], [[5ftu]] – hLAT-3 + FLRT2 + netrin receptor - human<br />
 +
**[[4rmk]], [[4rml]] – hLAT-3 olfactomedin domain 199-495<br />
 +
**[[5afb]] – hLAT-3 olfactomedin and lectin domains 97-495<br />
**[[5cmn]] – hLAT-3 olfactomedin domain + FLRT3<br />
**[[5cmn]] – hLAT-3 olfactomedin domain + FLRT3<br />
 +
**[[8djg]] – hLAT-3 residues 24-126 + antibody<br />
 +
**[[7wy5]], [[7wy8]], [[7wyb]] – hLAT-3 + nanobody + GS – Cryo EM<br />
 +
**[[7sf7]] – hLAT-3 residues 842-1138 + GS – Cryo EM<br />
 +
**[[7x10]] – hLAT-3 + Scfv + GS – Cryo EM<br />
**[[4yeb]] – mLAT-3 + FLRT3 <br />
**[[4yeb]] – mLAT-3 + FLRT3 <br />
-
**[[4rmk]], [[4rml]] – hLAT-3 olfactomedin domain<br />
+
**[[6jbu]] – mLAT-3 olfactomedin domain + FLRT3<br />
-
**[[5afb]] – hLAT-3 olfactomedin and lectin domains<br />
+
**[[6ska]], [[6ske]], [[6vhh]] – mLAT-3 olfactomedin domain + teneurin-2<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Human latrophilin-3 olfactomedin domain (magenta) complex with leucine-rich repeat transmembrane protein 3 (blue) and Ca+2 ion (green) (PDB code 5cmn)

Drag the structure with the mouse to rotate

3D structures of latrophilin

Updated on 18-June-2023

References

  1. ↑ Silva JP, Ushkaryov YA. The latrophilins, "split-personality" receptors. Adv Exp Med Biol. 2010;706:59-75. PMID:21618826
  2. ↑ Arcos-Burgos M, Jain M, Acosta MT, Shively S, Stanescu H, Wallis D, Domene S, Velez JI, Karkera JD, Balog J, Berg K, Kleta R, Gahl WA, Roessler E, Long R, Lie J, Pineda D, Londono AC, Palacio JD, Arbelaez A, Lopera F, Elia J, Hakonarson H, Johansson S, Knappskog PM, Haavik J, Ribases M, Cormand B, Bayes M, Casas M, Ramos-Quiroga JA, Hervas A, Maher BS, Faraone SV, Seitz C, Freitag CM, Palmason H, Meyer J, Romanos M, Walitza S, Hemminger U, Warnke A, Romanos J, Renner T, Jacob C, Lesch KP, Swanson J, Vortmeyer A, Bailey-Wilson JE, Castellanos FX, Muenke M. A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication. Mol Psychiatry. 2010 Nov;15(11):1053-66. doi: 10.1038/mp.2010.6. Epub 2010 Feb, 16. PMID:20157310 doi:http://dx.doi.org/10.1038/mp.2010.6
  3. ↑ Lu YC, Nazarko OV, Sando R 3rd, Salzman GS, Sudhof TC, Arac D. Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure. 2015 Jul 28. pii: S0969-2126(15)00277-4. doi:, 10.1016/j.str.2015.06.024. PMID:26235030 doi:http://dx.doi.org/10.1016/j.str.2015.06.024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Latrophilin"
Personal tools