7jlu
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ== | |
| - | + | <StructureSection load='7jlu' size='340' side='right'caption='[[7jlu]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7jlu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_benthamiana Nicotiana benthamiana] and [https://en.wikipedia.org/wiki/Xanthomonas_euvesicatoria Xanthomonas euvesicatoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JLU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jlu OCA], [https://pdbe.org/7jlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jlu RCSB], [https://www.ebi.ac.uk/pdbsum/7jlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jlu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ROQ1_NICBE ROQ1_NICBE] Disease resistance (R) protein that specifically recognizes the Xanthomonas and Pseudomonas effector proteins XopQ and HopQ1, and triggers cell death (PubMed:28891100). Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792).<ref>PMID:28891100</ref> <ref>PMID:31439792</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Nicotiana benthamiana]] | ||
| + | [[Category: Xanthomonas euvesicatoria]] | ||
| + | [[Category: King M]] | ||
| + | [[Category: Lui F]] | ||
| + | [[Category: Martin R]] | ||
| + | [[Category: Nogales E]] | ||
| + | [[Category: Qi T]] | ||
| + | [[Category: Staskawicz BJ]] | ||
| + | [[Category: Toth C]] | ||
| + | [[Category: Zhang H]] | ||
Current revision
Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ
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