6x4s

<StructureSection load='6x4s' size='340' side='right'caption='[[6x4s]], [[Resolution|resolution]] 3.50&Aring;' scene=''>

<table><tr><td colspan='2'>[[6x4s]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tribolium_castaneum Tribolium castaneum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X4S FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x4s OCA], [https://pdbe.org/6x4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x4s RCSB], [https://www.ebi.ac.uk/pdbsum/6x4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x4s ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/D6X268_TRICA D6X268_TRICA] Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.[RuleBase:RU369077][https://www.uniprot.org/uniprot/D6WIX5_TRICA D6WIX5_TRICA] Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.[RuleBase:RU367035]

==See Also==

*[[Mitochondrial calcium uniporter|Mitochondrial calcium uniporter]]

[[Category: Tribolium castaneum]]