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6lpc

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Current revision (14:42, 29 November 2023) (edit) (undo)
 
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<StructureSection load='6lpc' size='340' side='right'caption='[[6lpc]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<StructureSection load='6lpc' size='340' side='right'caption='[[6lpc]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6lpc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LPC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6LPC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6lpc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LPC FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Stxbp1, Unc18a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.402&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6lpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lpc OCA], [http://pdbe.org/6lpc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lpc RCSB], [http://www.ebi.ac.uk/pdbsum/6lpc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lpc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lpc OCA], [https://pdbe.org/6lpc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lpc RCSB], [https://www.ebi.ac.uk/pdbsum/6lpc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lpc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STXB1_RAT STXB1_RAT]] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
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[https://www.uniprot.org/uniprot/STXB1_RAT STXB1_RAT] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6lpc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6lpc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Syntaxin-binding protein|Syntaxin-binding protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gong, J H]]
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[[Category: Rattus norvegicus]]
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[[Category: Ma, C]]
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[[Category: Gong JH]]
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[[Category: Wang, S]]
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[[Category: Ma C]]
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[[Category: Wang, X P]]
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[[Category: Wang S]]
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[[Category: Xu, Y Y]]
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[[Category: Wang XP]]
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[[Category: Yang, X F]]
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[[Category: Xu YY]]
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[[Category: Yang, X Y]]
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[[Category: Yang XF]]
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[[Category: Zhu, L]]
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[[Category: Yang XY]]
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[[Category: Exocytosis]]
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[[Category: Zhu L]]
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[[Category: Membrane fusion]]
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[[Category: Snares-binding]]
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[[Category: Synaptic exocytosis]]
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Current revision

Crystal Structure of rat Munc18-1 with K332E/K333E mutation

PDB ID 6lpc

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