7jr7

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'''Unreleased structure'''
 
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The entry 7jr7 is ON HOLD until Paper Publication
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==Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4==
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<StructureSection load='7jr7' size='340' side='right'caption='[[7jr7]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7jr7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JR7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jr7 OCA], [https://pdbe.org/7jr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jr7 RCSB], [https://www.ebi.ac.uk/pdbsum/7jr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jr7 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN] Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
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Authors:
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==See Also==
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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Description:
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Huang CS]]
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[[Category: Min X]]
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[[Category: Wang Z]]
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[[Category: Yu X]]
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[[Category: Zhang H]]

Current revision

Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4

PDB ID 7jr7

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