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5t2r

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Current revision (15:35, 6 March 2024) (edit) (undo)
 
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<StructureSection load='5t2r' size='340' side='right'caption='[[5t2r]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5t2r' size='340' side='right'caption='[[5t2r]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5t2r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T2R OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5T2R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5t2r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T2R FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t2q|5t2q]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5t2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t2r OCA], [http://pdbe.org/5t2r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t2r RCSB], [http://www.ebi.ac.uk/pdbsum/5t2r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t2r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t2r OCA], [https://pdbe.org/5t2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t2r RCSB], [https://www.ebi.ac.uk/pdbsum/5t2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t2r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TNR14_HUMAN TNR14_HUMAN]] Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.<ref>PMID:8898196</ref>
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[https://www.uniprot.org/uniprot/TNR14_HUMAN TNR14_HUMAN] Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.<ref>PMID:8898196</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Nemcovicova, I]]
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[[Category: Nemcovicova I]]
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[[Category: Zajonc, D M]]
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[[Category: Zajonc DM]]
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[[Category: Herpesvirus entry mediator]]
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[[Category: Hvem]]
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[[Category: Immune system]]
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[[Category: Tnfrsf14]]
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Current revision

Unliganded Human HVEM at 2.1A in P 21 21 21

PDB ID 5t2r

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