This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7jsv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:53, 6 March 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='7jsv' size='340' side='right'caption='[[7jsv]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
<StructureSection load='7jsv' size='340' side='right'caption='[[7jsv]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7jsv]] is a 41 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JSV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7JSV FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7jsv]] is a 41 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JSV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JSV FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7jsv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jsv OCA], [http://pdbe.org/7jsv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7jsv RCSB], [http://www.ebi.ac.uk/pdbsum/7jsv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7jsv ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jsv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jsv OCA], [https://pdbe.org/7jsv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jsv RCSB], [https://www.ebi.ac.uk/pdbsum/7jsv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jsv ProSAT]</span></td></tr>
</table>
</table>
-
<div style="background-color:#fffaf0;">
+
== Function ==
-
== Publication Abstract from PubMed ==
+
[https://www.uniprot.org/uniprot/A6TIG0_KLEP7 A6TIG0_KLEP7]
-
Conjugative pili are important in mediating bacterial conjugation and horizontal gene transfer. Since plasmid transfer can include antibiotic-resistance genes, conjugation is an important mechanism in the spread of antibiotic resistance. Filamentous bacteriophages have been shown to exist in two different structural classes: those with a 5-fold rotational symmetry and those with a one-start helix with approximately 5 subunits per turn. Structures for the F and the F-like pED208 conjugation pilus have shown that they have 5-fold rotational symmetry. Here, we report the cryoelectron-microscopic structure of conjugative pili from carbapenem-resistant Klebsiella pneumoniae, encoded on the IncFIIK pKpQIL plasmid, at 3.9 A resolution and show that it has a one-start helix. These results establish that conjugation pili can exist in at least two structural classes, consistent with other results showing that relatively small perturbations are needed to change the helical symmetry of polymers.
+
-
Cryoelectron-Microscopic Structure of the pKpQIL Conjugative Pili from Carbapenem-Resistant Klebsiella pneumoniae.,Zheng W, Pena A, Low WW, Wong JLC, Frankel G, Egelman EH Structure. 2020 Sep 8. pii: S0969-2126(20)30292-6. doi:, 10.1016/j.str.2020.08.010. PMID:32916103<ref>PMID:32916103</ref>
+
==See Also==
-
 
+
*[[Pilin 3D structures|Pilin 3D structures]]
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 7jsv" style="background-color:#fffaf0;"></div>
+
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Egelman, E H]]
+
[[Category: Egelman EH]]
-
[[Category: Frankel, G]]
+
[[Category: Frankel G]]
-
[[Category: Pena, A]]
+
[[Category: Pena A]]
-
[[Category: Zheng, W]]
+
[[Category: Zheng W]]
-
[[Category: Conjugation pili]]
+
-
[[Category: Helical reconstruction]]
+
-
[[Category: Protein fibril]]
+

Current revision

Cryo-EM structure of conjugative pili from carbapenem-resistant Klebsiella pneumoniae

PDB ID 7jsv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7jsv"
Personal tools