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5tuo

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Current revision (13:12, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5tuo' size='340' side='right'caption='[[5tuo]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='5tuo' size='340' side='right'caption='[[5tuo]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tuo]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TUO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5TUO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tuo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TUO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1SA:5-AMINO-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>1SA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tt3|5tt3]], [[5tt8|5tt8]], [[5tv3|5tv3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1SA:5-AMINO-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>1SA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tuo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tuo OCA], [https://pdbe.org/5tuo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tuo RCSB], [https://www.ebi.ac.uk/pdbsum/5tuo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tuo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5tuo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tuo OCA], [http://pdbe.org/5tuo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tuo RCSB], [http://www.ebi.ac.uk/pdbsum/5tuo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tuo ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0M3KL20_HELPY A0A0M3KL20_HELPY]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carbonate dehydratase]]
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[[Category: Helicobacter pylori 26695]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Modak, J K]]
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[[Category: Modak JK]]
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[[Category: Roujeinikova, A]]
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[[Category: Roujeinikova A]]
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[[Category: 4-thiadiazole-2-sulfonamide]]
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[[Category: 5-amino-1]]
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[[Category: Alpha-carbonic anhydrase]]
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[[Category: Helicobacter pylori]]
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[[Category: Lyase]]
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[[Category: Lyase-lyase inhibitor complex]]
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[[Category: Zinc metalloenzyme]]
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Current revision

Crystal structure of the complex of Helicobacter pylori alpha-carbonic anhydrase with 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.

PDB ID 5tuo

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