Phycocyanobilin:ferredoxin oxidoreductase

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Current revision (10:02, 30 August 2023) (edit) (undo)
 
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[[2d1e]], [[4qcd]] – SyPcyA + biliverdin IX<br />
[[2d1e]], [[4qcd]] – SyPcyA + biliverdin IX<br />
[[3ajg]], [[3i95]], [[4eoc]], [[4eod]], [[4eoe]], [[5b4h]], [[5b4i]], [[5b4j]] – SyPcyA (mutant) + biliverdin IX<br />
[[3ajg]], [[3i95]], [[4eoc]], [[4eod]], [[4eoe]], [[5b4h]], [[5b4i]], [[5b4j]] – SyPcyA (mutant) + biliverdin IX<br />
 +
[[7yk9]], [[7ykb]] – SyPcyA (mutant) + biliverdin IX – Neutron<br />
[[3i94]] - SyPcyA + biliverdin XIII<br />
[[3i94]] - SyPcyA + biliverdin XIII<br />
[[3ajh]] – SyPcyA (mutant) + biliverdin XIII<br />
[[3ajh]] – SyPcyA (mutant) + biliverdin XIII<br />

Current revision

Phycocyanobilin:ferredoxin oxidoreductase complex with biliverdin IX-α (PDB entry 3ajg)

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3D Structures of Phycocyanobilin:ferredoxin oxidoreductase

Updated on 30-August-2023

2dke – SyPcyA – Synechocystis
3f0l, 3f0m, 3nb8, 3nb9 – SyPcyA (mutant)
2d1e, 4qcd – SyPcyA + biliverdin IX
3ajg, 3i95, 4eoc, 4eod, 4eoe, 5b4h, 5b4i, 5b4j – SyPcyA (mutant) + biliverdin IX
7yk9, 7ykb – SyPcyA (mutant) + biliverdin IX – Neutron
3i94 - SyPcyA + biliverdin XIII
3ajh – SyPcyA (mutant) + biliverdin XIII
3i8u – SyPcyA + biliverdin derivative
2g18 – PcyA – Anabena

References

  1. Tu SL, Gunn A, Toney MD, Britt RD, Lagarias JC. Biliverdin reduction by cyanobacterial phycocyanobilin:ferredoxin oxidoreductase (PcyA) proceeds via linear tetrapyrrole radical intermediates. J Am Chem Soc. 2004 Jul 21;126(28):8682-93. PMID:15250720 doi:http://dx.doi.org/10.1021/ja049280z
  2. Wada K, Hagiwara Y, Yutani Y, Fukuyama K. One residue substitution in PcyA leads to unexpected changes in tetrapyrrole substrate binding. Biochem Biophys Res Commun. 2010 Nov 12;402(2):373-7. Epub 2010 Oct 12. PMID:20946883 doi:10.1016/j.bbrc.2010.10.037

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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