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6v04
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==DynU16 crystal structure, a putative protein in the dynemicin biosynthetic locus== | |
| + | <StructureSection load='6v04' size='340' side='right'caption='[[6v04]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6v04]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Micromonospora_chersina Micromonospora chersina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V04 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v04 OCA], [https://pdbe.org/6v04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v04 RCSB], [https://www.ebi.ac.uk/pdbsum/6v04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v04 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B2BM46_9ACTN B2BM46_9ACTN] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The 1.5 A resolution crystal structure of DynU16, a protein identified in the dynemicin-biosynthetic gene cluster, is reported. The structure adopts a di-domain helix-grip fold with a uniquely positioned open cavity connecting the domains. The elongated dimensions of the cavity appear to be compatible with the geometry of a linear polyene, suggesting the involvement of DynU16 in the upstream steps of dynemicin biosynthesis. | ||
| - | + | Structural characterization of DynU16, a START/Bet v1-like protein involved in dynemicin biosynthesis.,Alvarado SK, Miller MD, Bhardwaj M, Thorson JS, Van Lanen SG, Phillips GN Jr Acta Crystallogr F Struct Biol Commun. 2021 Oct 1;77(Pt 10):328-333. doi:, 10.1107/S2053230X21008943. Epub 2021 Sep 21. PMID:34605436<ref>PMID:34605436</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: | + | <div class="pdbe-citations 6v04" style="background-color:#fffaf0;"></div> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Thorson | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Micromonospora chersina]] |
| + | [[Category: Alvarado SK]] | ||
| + | [[Category: Bhardwaj M]] | ||
| + | [[Category: Miller MD]] | ||
| + | [[Category: Phillips Jr GN]] | ||
| + | [[Category: Thorson JS]] | ||
| + | [[Category: Van Lanen SG]] | ||
Current revision
DynU16 crystal structure, a putative protein in the dynemicin biosynthetic locus
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