3kin

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Current revision (09:48, 25 December 2024) (edit) (undo)
 
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<StructureSection load='3kin' size='340' side='right'caption='[[3kin]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='3kin' size='340' side='right'caption='[[3kin]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kin]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. The April 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Kinesin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_4 10.2210/rcsb_pdb/mom_2005_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3KIN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kin]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The April 2005 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Kinesin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2005_4 10.2210/rcsb_pdb/mom_2005_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KIN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3kin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kin OCA], [http://pdbe.org/3kin PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kin RCSB], [http://www.ebi.ac.uk/pdbsum/3kin PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kin ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kin OCA], [https://pdbe.org/3kin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kin RCSB], [https://www.ebi.ac.uk/pdbsum/3kin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kin ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KIF5C_RAT KIF5C_RAT] Microtubule-associated force-producing protein that may play a role in organelle transport (By similarity). Has ATPase activity (PubMed:27452403). Involved in synaptic transmission (By similarity). Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (PubMed:23576431).[UniProtKB:O60282][UniProtKB:P28738]<ref>PMID:23576431</ref> <ref>PMID:27452403</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ki/3kin_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ki/3kin_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
 
[[Category: Kinesin]]
[[Category: Kinesin]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Biou, V]]
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[[Category: Rattus norvegicus]]
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[[Category: Kozielski, F]]
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[[Category: Biou V]]
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[[Category: Mandelkow, E]]
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[[Category: Kozielski F]]
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[[Category: Mandelkow, E M]]
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[[Category: Mandelkow E]]
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[[Category: Marx, A]]
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[[Category: Mandelkow E-M]]
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[[Category: Sack, S]]
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[[Category: Marx A]]
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[[Category: Schonbrunn, E]]
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[[Category: Sack S]]
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[[Category: Thompson, A]]
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[[Category: Schonbrunn E]]
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[[Category: Thormahlen, M]]
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[[Category: Thompson A]]
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[[Category: Cytoskeleton]]
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[[Category: Thormahlen M]]
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[[Category: Motor protein]]
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Current revision

KINESIN (DIMERIC) FROM RATTUS NORVEGICUS

PDB ID 3kin

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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