Protein G

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Protein G domain II (grey) complex with mouse Fab heavy chain (red) and light chain (aqua) (PDB code 1uwx).

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Updated on 03-February-2022

↑ Erntell M, Myhre EB, Sjobring U, Bjorck L. Streptococcal protein G has affinity for both Fab- and Fc-fragments of human IgG. Mol Immunol. 1988 Feb;25(2):121-6. PMID:3131664

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 <StructureSection load='1uwx' size='340' side='right' caption='Protein G domain II (grey) complex with mouse Fab heavy chain (red) and light chain (aqua) (PDB code [[1uwx]]).' scene=''>
-'''Protein G''' (ProG) is a cell surface protein from Streptococcal bacteria which binds Fab and Fc regions of immunoglobulins<ref>PMID:3131664</ref>.
+'''Protein G''' or '''immunoglobulin-binding protein G''' (ProG) is a cell surface protein from Streptococcal bacteria which binds Fab and Fc regions of immunoglobulins<ref>PMID:3131664</ref>.
 For ProG  immunoglobulin-binding domain see [[Chameleon peptide]].
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 **[[3fil]], [[1pgx]], [[2igd]], [[1igd]] - StProG <br />
-**[[3v3x]], [[5bmg]], [[6cte]] – StProG (mutant) <br />
+**[[3v3x]], [[5bmg]], [[6c9o]], [[6cte]], [[6nl6]], [[6nl7]], [[6nl8]], [[6nl9]], [[6nlb]] – StProG (mutant) <br />
 **[[2plp]], [[1p7f]], [[1p7e]], [[2n7j]], [[2lum]] - StProG - NMR<br />
 **[[2jsv]], [[2kq4]], [[2kwd]], [[1fcl]], [[1fd6]] - StProG (mutant) - NMR<br />
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 **[[2igh]] – StProG – NMR<br />
 **[[2onq]], [[2on8]] – StProG (mutant) <br />
-**[[1gb4]] – StProG (mutant) – NMR<br />
+**[[1gb4]], [[6njf]] – StProG (mutant) – NMR<br />
 **[[1fcc]] – StProG + Igg1 Fc<br />