Pyridoxal kinase
From Proteopedia
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**[[2f7k]] – hPDX - human<br /> | **[[2f7k]] – hPDX - human<br /> | ||
**[[1lhp]] – sPDX – sheep<br /> | **[[1lhp]] – sPDX – sheep<br /> | ||
+ | **[[6yjz]] – mPDX - mouse<br /> | ||
**[[2ddm]] – EcPDX1 – ''Escherichia coli''<br /> | **[[2ddm]] – EcPDX1 – ''Escherichia coli''<br /> | ||
**[[3h74]] – LpPDX – ''Lactobacillus planarum'' <br /> | **[[3h74]] – LpPDX – ''Lactobacillus planarum'' <br /> | ||
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**[[5trw]] - PDX - ''Burkholderia xenovorans''<br /> | **[[5trw]] - PDX - ''Burkholderia xenovorans''<br /> | ||
**[[5b6a]] - PDX - ''Pseudomonas aeruginosa''<br /> | **[[5b6a]] - PDX - ''Pseudomonas aeruginosa''<br /> | ||
- | **[[5zw9]] – | + | **[[5zw9]] – ScPDX – ''Salmonella choleraesuis''<br /> |
*Pyridoxal kinase complex with pyridoxal compounds | *Pyridoxal kinase complex with pyridoxal compounds | ||
- | **[[3fhx]] – hPDX (mutant) + Mg + Na + ATP + pyridoxal + | + | **[[3fhx]] – hPDX (mutant) + Mg + Na + ATP + pyridoxal + PLP <br /> |
- | **[[3keu]] – hPDX + Mg + ATP + | + | **[[3keu]] – hPDX + Mg + ATP + PLP<br /> |
**[[1rft]] – sPDX + Zn + K + AMPPCP + pyridoxamine<br /> | **[[1rft]] – sPDX + Zn + K + AMPPCP + pyridoxamine<br /> | ||
- | **[[1rfu]] – sPDX + Zn + ADP + | + | **[[1rfu]] – sPDX + Zn + ADP + PLP<br /> |
**[[2ddw]] – EcPDX1 + pyridoxal<br /> | **[[2ddw]] – EcPDX1 + pyridoxal<br /> | ||
**[[4c5l]] – SaPDX + pyridoxal<br /> | **[[4c5l]] – SaPDX + pyridoxal<br /> | ||
**[[4c5n]] – SaPDX + pyridoxal + AMPPCP<br /> | **[[4c5n]] – SaPDX + pyridoxal + AMPPCP<br /> | ||
- | **[[4s1i]] – EhPDX + Mg + | + | **[[4s1i]] – EhPDX + Mg + PLP - ''Entamoeba histolytica'' <br /> |
**[[6su9]] – PDX + pyridoxal + AMPPNP – ''Plasmodium falciparum''<br /> | **[[6su9]] – PDX + pyridoxal + AMPPNP – ''Plasmodium falciparum''<br /> | ||
**[[6k91]], [[6k92]] – LdPDX + ADP + pyridoxine derivative – ''Leishmania donovani''<br /> | **[[6k91]], [[6k92]] – LdPDX + ADP + pyridoxine derivative – ''Leishmania donovani''<br /> | ||
**[[6k90]] – LdPDX + ADP + pyridoxamine <br /> | **[[6k90]] – LdPDX + ADP + pyridoxamine <br /> | ||
+ | **[[5zwa]], [[5zwb]] – ScPDX + ADP + PLP<br /> | ||
*Other pyridoxal kinase complexes | *Other pyridoxal kinase complexes | ||
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**[[1rfv]] – sPDX + Zn + ADP <br /> | **[[1rfv]] – sPDX + Zn + ADP <br /> | ||
**[[1ygj]], [[1ygk]], [[1yhj]] – sPDX + roscovitine<br /> | **[[1ygj]], [[1ygk]], [[1yhj]] – sPDX + roscovitine<br /> | ||
+ | **[[6yk0]] – mPDX + ATPgS <br /> | ||
+ | **[[6yk1]] – mPDX + ATPgS + artesunate<br /> | ||
**[[2ddo]] – EcPDX1 + Mg + ATP + Pi<br /> | **[[2ddo]] – EcPDX1 + Mg + ATP + Pi<br /> | ||
**[[2i5b]] – PDX + ADP – ''Bacillus subtilis''<br /> | **[[2i5b]] – PDX + ADP – ''Bacillus subtilis''<br /> |
Current revision
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3D Structures of pyridoxal kinase
Updated on 04-October-2023
References
- ↑ di Salvo ML, Nogues I, Parroni A, Tramonti A, Milano T, Pascarella S, Contestabile R. On the mechanism of Escherichia coli pyridoxal kinase inhibition by pyridoxal and pyridoxal 5'-phosphate. Biochim Biophys Acta. 2015 Sep;1854(9):1160-6. doi: 10.1016/j.bbapap.2015.01.013., Epub 2015 Feb 3. PMID:25655354 doi:http://dx.doi.org/10.1016/j.bbapap.2015.01.013
- ↑ Safo MK, Musayev FN, di Salvo ML, Hunt S, Claude JB, Schirch V. Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases. J Bacteriol. 2006 Jun;188(12):4542-52. PMID:16740960 doi:188/12/4542