7kc6

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'''Unreleased structure'''
 
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The entry 7kc6 is ON HOLD until sometime in the future
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==X-ray structure of Lfa-1 I domain in complex with Lovastatin collected at 273 K==
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<StructureSection load='7kc6' size='340' side='right'caption='[[7kc6]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7kc6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KC6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=803:LOVASTATIN'>803</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kc6 OCA], [https://pdbe.org/7kc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kc6 RCSB], [https://www.ebi.ac.uk/pdbsum/7kc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kc6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
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Authors: Woldeyes, R.A., Hallenbeck, K.K., Pfaff, S.J., Lee, G., Cortez, S.V., Kelly, M.J., Akassoglou, K., Arkin, M.R., Fraser, J.S.
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==See Also==
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*[[Integrin 3D structures|Integrin 3D structures]]
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Description: X-ray structure of Lfa-1 I domain in complex with Lovastatin collected at 273 K
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Akassoglou, K]]
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[[Category: Homo sapiens]]
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[[Category: Cortez, S.V]]
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[[Category: Large Structures]]
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[[Category: Woldeyes, R.A]]
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[[Category: Akassoglou K]]
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[[Category: Hallenbeck, K.K]]
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[[Category: Arkin MR]]
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[[Category: Kelly, M.J]]
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[[Category: Cortez SV]]
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[[Category: Arkin, M.R]]
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[[Category: Fraser JS]]
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[[Category: Fraser, J.S]]
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[[Category: Hallenbeck KK]]
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[[Category: Lee, G]]
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[[Category: Kelly MJ]]
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[[Category: Pfaff, S.J]]
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[[Category: Lee G]]
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[[Category: Pfaff SJ]]
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[[Category: Woldeyes RA]]

Current revision

X-ray structure of Lfa-1 I domain in complex with Lovastatin collected at 273 K

PDB ID 7kc6

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