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5xj4
From Proteopedia
(Difference between revisions)
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<StructureSection load='5xj4' size='340' side='right'caption='[[5xj4]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='5xj4' size='340' side='right'caption='[[5xj4]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5xj4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJ4 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5xj4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XJ4 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xj4 OCA], [https://pdbe.org/5xj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xj4 RCSB], [https://www.ebi.ac.uk/pdbsum/5xj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xj4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chai | + | [[Category: Chai Y]] |
| - | [[Category: Gao | + | [[Category: Gao GF]] |
| - | [[Category: Liu | + | [[Category: Liu K]] |
| - | [[Category: Qi | + | [[Category: Qi J]] |
| - | [[Category: Tan | + | [[Category: Tan S]] |
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Current revision
Complex structure of durvalumab-scFv/PD-L1
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Categories: Homo sapiens | Large Structures | Chai Y | Gao GF | Liu K | Qi J | Tan S
