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Pre-mRNA splicing factors 3D structures
From Proteopedia
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**[[3beg]] – hPrp P33 subunit + Ser/Thr-protein kinase – human<BR /> | **[[3beg]] – hPrp P33 subunit + Ser/Thr-protein kinase – human<BR /> | ||
| - | **[[2o3d]] – hPrp P33 subunit | + | **[[2o3d]] – hPrp P33 subunit<br /> |
| + | **[[7dcq]] – yPrp – yeast – Cryo EM<br /> | ||
| + | **[[7dcr]] – yPrp + Prp spp2 – Cryo EM<br /> | ||
| + | **[[7dd3]] – yPrp + Prp spp2 + RNA – Cryo EM<br /> | ||
| + | **[[7dcp]] – yPrp + Prp spp2 + ADP – Cryo EM<br /> | ||
*Pre-mRNA-splicing factor 3 | *Pre-mRNA-splicing factor 3 | ||
**[[1x4q]] – hPrp PWI domain - NMR<BR /> | **[[1x4q]] – hPrp PWI domain - NMR<BR /> | ||
| - | **[[4yhu]], [[4yhv]] – yPrp C-terminal | + | **[[4yhu]], [[4yhv]] – yPrp C-terminal<br /> |
**[[4yhw]] – yPrp C-terminal + snRNA<br /> | **[[4yhw]] – yPrp C-terminal + snRNA<br /> | ||
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**[[4jk7]], [[4jk9]], [[3e9o]], [[3e9p]], [[3e66]] - yPrp RNAse H like domain <br /> | **[[4jk7]], [[4jk9]], [[3e9o]], [[3e9p]], [[3e66]] - yPrp RNAse H like domain <br /> | ||
**[[4ilj]], [[4jk8]], [[4jka]], [[4jkb]], [[4jkc]], [[4jkd]], [[4jke]], [[4jkf]], [[4jkg]], [[4jkh]] - yPrp RNAse H like domain (mutant)<br /> | **[[4ilj]], [[4jk8]], [[4jka]], [[4jkb]], [[4jkc]], [[4jkd]], [[4jke]], [[4jkf]], [[4jkg]], [[4jkh]] - yPrp RNAse H like domain (mutant)<br /> | ||
| - | **[[ | + | **[[5qy1]], [[5qy2]], [[5qy3]], [[5qy4]], [[5qy5]], [[5qy6]], [[5qy7]], [[5qy8]], [[5qy9]], [[5qya]], [[5qyb]], [[5qyc]], [[5qyd]], [[5qye]], [[5qyf]], [[5qyg]], [[5qyh]], [[5qyi]], [[5qyj]], [[5qyk]], [[5qyl]], [[5qyn]], [[5qyo]], [[5qyp]], [[5qyq]], [[5qyr]], [[5qys]], [[5qyt]], [[5qyu]], [[5qyy]], [[5qyw]], [[5qyx]], [[5qyz]], [[5qz0]], [[5qz1]], [[5qz2]], [[5qz3]], [[5qz4]], [[5qz5]], [[5qz6]], [[5qz7]], [[5qz8]], [[5qz9]], [[5qza]], [[5qzb]], [[5qzc]], [[5qzd]], [[5qze]], [[5qzf]], [[5qzg]], [[5qzi]], [[5qzj]], [[5qzk]], [[5qzl]], [[5qzm]], [[5qzn]], [[5qzo]], [[5qzp]], [[5qzq]], [[5qzr]], [[5qzs]], [[5qzt]], [[5qzu]], [[5qzv]], [[5qzw]], [[5qzx]], [[5qzy]], [[5qzz]], [[5r00]], [[5r01]], [[5r03]], [[5r04]], [[5r05]], [[5r06]][[5r07]], [[5r08]], [[5r09]], [[5r0a]], [[5r0b]], [[5r0c]], [[5r0d]], [[5r0e]], [[5r0f]], [[5r0g]], [[5r0h]], [[5r0i]], [[5r0j]], [[5r0k]], [[5r0l]], [[5r0m]], [[5r0n]], [[5r0o]], [[5r0p]], [[5r0q]], [[5r0r]], [[5r0s]], [[[5r0t]], [[5r0u]], [[5r0x]], [[5r0y]], [[5r0z]], [[5r10]], [[5r11]], [[5r12]], [[5r13]], [[5r14]], [[5r15]], [[5r16]], [[5r17]], [[5r18]], [[5r19]], [[5r1a]], [[5r1b]], [[5r1c]], [[5r1d]], [[5r1e]], [[5r1f]], [[5r1g]], [[5r1h]], [[5r1i]], [[5r1j]], [[5r1l]], [[5r1k]], [[5r1m]], [[5r1n]], [[5r1p]], [[5r1q]], [[5r1s]], [[5st0]], [[5st1]], [[5st2]], [[5st3]], [[5st4]], [[5st5]], [[5st6]], [[5st7]], [[5st8]], [[5st9]], [[5sta]], [[5stb]], [[5stc]], [[5ste]], [[5stf]], [[5stg]], [[5sth]], [[5sti]], [[5stj]], [[5stk]], [[5stl]], [[5stm]], [[5stn]], [[5sto]], [[5stp]], [[5stq]], [[5str]], [[5sts]], [[5stt]], [[5stu]], [[5stv]], [[5stw]], [[5stx]], [[5sty]], [[6stz]], [[5su0]], [[5su1]], [[5su2]], [[5su3]], [[5su4]], [[5su5]], [[5su6]], [[5su7]], [[5su8]], [[5su9]], [[5sua]], [[5sub]], [[5suc]], [[5sud]], [[5sue]], [[5suf]], [[5sug]], [[7fju]], [[7fjv]], [[7fjw]], [[7fjx]], [[7fjy]], [[7fjz]], [[7fk0]], [[7fk1]], [[7fk2]], [[7fk3]], [[7fk4]], [[7fk5]],[[7fk6]], [[7fk7]], [[7fk8]], [[7fk9]], [[7fka]], [[7fkb]], [[7fkc]], [[7fkd]], [[7fke]], [[7fkf]], [[7fkg]], [[7fkh]], [[7fki]],[[7fkj]], [[7fkk]], [[7fkl]], [[7fkm]], [[7fkn]], [[7fko]], [[7fkp]], [[7fkq]], [[7fkr]], [[7fks]], [[7fkt]], [[7fku]], [[7fkv]], [[7fkw]], [[7fkx]], [[7fky]], [[7fkz]], [[7fl0]], [[7fl1]], [[7fl2]], [[7fl3]], [[7fl4]], [[7fl5]], [[7fl6]], [[7fl7]], [[7fl8]], [[7fl9]], [[7fla]], [[7flb]], [[7fld]], [[7fle]], [[7flf]], [[7flg]], [[7flh]], [[7fli]], [[7flj]], [[7flk]], [[7fll]], [[7flm]], [[7fln]], [[7flo]], [[7flp]], [[7flq]], [[7flr]], [[7fls]], [[7flt]], [[7flu]], [[7flv]], [[7flw]], [[7flx]], [[7fly]], [[7flz]], [[7fm0]], [[7fm1]], [[7fm2]], [[7fm3]], [[7fm4]], [[7fm5]], [[7fm6]], [[7fm7]], [[7fm8]], [[7fm9]], [[7fma]], [[7fmb]], [[7fmc]], [[7fmd]], [[7fme]], [[7fmf]], [[7fmg]], [[7fmh]], [[7fmi]], [[7fmk]], [[7fml]], [[7fmm]], [[7fmn]], [[7fmo]], [[7fmp]], [[7fmq]], [[7fmr]], [[7fms]], [[7fmt]], [[7fmu]], [[7fmv]], [[7fmw]], [[7fmx]], [[7fmy]], [[7fmz]], [[7fn0]], [[7fn1]], [[7fn2]], [[7fn3]], [[7fn4]], [[7fn5]], [[7fn6]], [[7fn7]], [[7fn8]], [[7fn9]], [[7fna]], [[7fnb]], [[7fnc]], [[7fnd]], [[7fne]], [[7fnf]], [[7fng]], [[7fnh]], [[7fni]], [[7fnj]], [[7fnk]], [[7fnl]], [[7fnm]], [[7fnn]], [[7fno]], [[7fnp]], [[7fnq]], [[7fnr]], [[7fns]], [[7fnt]], [[7fnu]], [[7fnv]], [[7fnw]], [[7fnx]], [[7fny]], [[7fnz]], [[7fo0]], [[7fo1]], [[7fo2]], [[7fo3]], [[7fo4]], [[7fo5]], [[7fo6]], [[7fo7]], [[7fo9]], [[7foa]], [[7fob]], [[7foc]], [[7fod]], [[7foe]], [[7fof]], [[7fog]], [[7foh]], [[7foi]], [[7foj]], [[7fok]], [[7fol]], [[7fom]], [[7fon]], [[7foo]], [[7fop]], [[7foq]], [[7for]], [[7fos]], [[7fot]], [[7fou]], [[7fov]], [[7fow]], [[7fox]], [[7foy]], [[7foz]], [[7fp0]], [[7fp1]], [[7fp2]], [[7fp3]], [[[7fp4]], [[7fp5]], [[7fp6]], [[7fp7]], [[7fp8]], [[7fp9]], [[7fpa]], [[7fpb]], [[7fpc]], [[7fpd]], [[7fpe]], [[7fpf]], [[7fpg]], [[7fph]], [[7fpi]], [[7fpj]], [[7fpk]] – yPrp H-like domain + A1 cistron-splicing factor AAR2<br />885-2413 |
| - | **[[ | + | **[[3zef]], [[4i43]] 885-2413 – yPrp + A1 cistron-splicing factor AAR2<br /> |
| + | **[[2og4]] - yPrp Jab1/MPN domain 2147-2397<br /> | ||
**[[4bgd]], [[5dca]], [[5m52]], [[5m5p]] – yPrp Jab1/MPN domain + pre-mRNA-splicing helicase BRR2<br /> | **[[4bgd]], [[5dca]], [[5m52]], [[5m5p]] – yPrp Jab1/MPN domain + pre-mRNA-splicing helicase BRR2<br /> | ||
| + | **[[3sbg]] - yPrp C-terminal domain 1836-2397<br /> | ||
**[[4kit]] – yPrp Jab1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br /> | **[[4kit]] – yPrp Jab1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br /> | ||
**[[4ilg]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 <br /> | **[[4ilg]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 <br /> | ||
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*Pre-mRNA-splicing factor 40 | *Pre-mRNA-splicing factor 40 | ||
| - | **[[1o6w]] – yPrp WW domain | + | **[[1o6w]] – yPrp WW domain - NMR<br /> |
**[[2b7e]] – yPrp FF1 domain - NMR<br /> | **[[2b7e]] – yPrp FF1 domain - NMR<br /> | ||
**[[2kfd]] – yPrp FF4 domain - NMR<br /> | **[[2kfd]] – yPrp FF4 domain - NMR<br /> | ||
| - | *Pre-mRNA-splicing factor 43P | + | *Pre-mRNA-splicing factor 43P or Pre-mRNA-splicing factor ATP-dependent RNA helicase Prp43 |
| - | **[[2xau]], [[3kx2]] – yPrp + ADP | + | **[[2xau]], [[3kx2]] – yPrp + ADP<br /> |
| + | **[[5jpt]] – yPrp + CDP<br /> | ||
| + | **[[5i8q]] – yPrp + ADPNP + RNA<br /> | ||
| + | **[[5d0u]], [[5ltj]], [[5ltk]] – TtPrp + ADP – ''Thermochaetoides thermophila''<br /> | ||
| + | **[[5lta]] – TtPrp + ADP + RNA<br /> | ||
| - | *Pre-mRNA-splicing factors in spliceosome | + | *Pre-mRNA-splicing factors in spliceosome or C* complex |
| - | **[[3jcr]], [[5o9z]], [[ | + | **[[3jcr]], [[5o9z]], [[5xjc]], [[5yzg]], [[5z56]], [[5z57]], [[5z58]], [[6ah0]], [[6ahd]], [[6ff4]], [[6ff7]], [[6icz]], [[6id0]], [[6id1]], [[6qdv]], [[6qw6]], [[6qx9]], [[6y50]], [[6y53]], [[6y5q]], [[6zym]], [[7a5p]], [[7aav]], [[7abf]], [[7abg]], [[7abh]], [[7abi]], [[7dvq]], [[7evo]], [[7onb]], [[7q4o]], [[7q4p]], [[7qtt]], [[7vpx]], [[7w59]], [[7w5a]], [[7w5b]], [[8c6j]], [[8ch6]], [[8hk1]] – hPrp - CryoEM<br /> |
**[[3jb9]] – yPrp <br /> | **[[3jb9]] – yPrp <br /> | ||
| - | **[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5wsg]], [[6g90]], [[6exn]], [[6bk8]], [[5ylz]], [[5y88]], [[6j6q]], [[6j6n]], [[6j6h]], [[6j6g]], [[5zwo]] – yPrp - CryoEM<br /> | + | **[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gm6]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5nrl]], [[5wsg]], [[6g90]], [[6exn]], [[6bk8]], [[5ylz]], [[5y88]], [[6j6q]], [[6j6n]], [[6j6h]], [[6j6g]], [[5zwo]], [[7b9v]], [[7dco]], [[7oqb]], [[7oqe]] – yPrp - CryoEM<br /> |
*Pre-mRNA-splicing factor cwc2 | *Pre-mRNA-splicing factor cwc2 | ||
**[[3tp2]], [[3u1l]], [[3u1m]] – yPrp <br /> | **[[3tp2]], [[3u1l]], [[3u1m]] – yPrp <br /> | ||
| + | |||
| + | *Pre-mRNA-splicing factor cwc22 | ||
| + | |||
| + | **[[6yvh]] – hPrp + cwc27 + EIF-4A<br /> | ||
| + | **[[4c9b]] – yPrp 116-406 + EIF-4A<br /> | ||
*Pre-mRNA-splicing factor cwc26 | *Pre-mRNA-splicing factor cwc26 | ||
| + | **[[2my2]] – yPrp 215-255 + U2 SNRNP component IST3 - NMR<br /> | ||
**[[2mkc]] – yPrp + U2 SNRNP component IST3 + Pre-mRNA leakage protein<br /> | **[[2mkc]] – yPrp + U2 SNRNP component IST3 + Pre-mRNA leakage protein<br /> | ||
**[[4uqt]] – yPrp + U2 SNRNP component IST3 <br /> | **[[4uqt]] – yPrp + U2 SNRNP component IST3 <br /> | ||
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**[[2my1]] – yPrp - NMR<br /> | **[[2my1]] – yPrp - NMR<br /> | ||
| + | *Pre-mRNA-splicing factor cef1 | ||
| + | |||
| + | **[[6jui]] – Prp – rice fungus <br /> | ||
*Pre-mRNA-splicing factor sad1 | *Pre-mRNA-splicing factor sad1 | ||
Current revision
3D Structures of pre-mRNA splicing factors
Updated on 11-September-2023
