6zgl

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==Structure of DPS determined by movement-free cryoEM with zero dose extrapolation==
==Structure of DPS determined by movement-free cryoEM with zero dose extrapolation==
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<StructureSection load='6zgl' size='340' side='right'caption='[[6zgl]]' scene=''>
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<StructureSection load='6zgl' size='340' side='right'caption='[[6zgl]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZGL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ZGL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6zgl]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZGL FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6zgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zgl OCA], [http://pdbe.org/6zgl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6zgl RCSB], [http://www.ebi.ac.uk/pdbsum/6zgl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6zgl ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zgl OCA], [https://pdbe.org/6zgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zgl RCSB], [https://www.ebi.ac.uk/pdbsum/6zgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zgl ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPS_ECOLI DPS_ECOLI] During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and copper toxicity, thermal stress and acid and base shocks. Also shows a weak catalase activity.<ref>PMID:1340475</ref> <ref>PMID:10403254</ref> <ref>PMID:15205421</ref> <ref>PMID:15534364</ref>
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==See Also==
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*[[Ferritin 3D structures|Ferritin 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Naydenova K]]
[[Category: Naydenova K]]
[[Category: Russo CJ]]
[[Category: Russo CJ]]

Current revision

Structure of DPS determined by movement-free cryoEM with zero dose extrapolation

PDB ID 6zgl

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