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3mvg

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<StructureSection load='3mvg' size='340' side='right'caption='[[3mvg]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='3mvg' size='340' side='right'caption='[[3mvg]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mvg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Iris_hollandica Iris hollandica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3MVG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mvg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Iris_x_hollandica Iris x hollandica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MVG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b7u|2b7u]], [[1bry|1bry]], [[1ahc|1ahc]], [[1nio|1nio]], [[1rl0|1rl0]], [[2oqa|2oqa]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mvg OCA], [https://pdbe.org/3mvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mvg RCSB], [https://www.ebi.ac.uk/pdbsum/3mvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mvg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3mvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mvg OCA], [http://pdbe.org/3mvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mvg RCSB], [http://www.ebi.ac.uk/pdbsum/3mvg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mvg ProSAT]</span></td></tr>
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</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/O04358_IRIHO O04358_IRIHO]
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The most abundant protein of Iris bulbs has been identified as a type 1 ribosome-inactivating protein (RIP). Analysis of the purified proteins and molecular cloning of the corresponding cDNAs demonstrated that this type 1 RIP is a mixture of three isoforms that exhibit a high degree of sequence identity and have similar, though not identical, ribosome-inactivating and polynucleotide:adenosine glycosidase activities. The accumulation of large quantities of type 1 RIP in a vegetative storage organ suggests that this presumed defence-related protein also plays a role in the nitrogen-storage metabolism of the bulb.
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Type 1 ribosome-inactivating proteins are the most abundant proteins in iris (Iris hollandica var. Professor Blaauw) bulbs: characterization and molecular cloning.,Van Damme EJ, Barre A, Barbieri L, Valbonesi P, Rouge P, Van Leuven F, Stirpe F, Peumans WJ Biochem J. 1997 Jun 15;324 ( Pt 3):963-70. PMID:9210423<ref>PMID:9210423</ref>
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==See Also==
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*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3mvg" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Iris hollandica]]
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[[Category: Iris x hollandica]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: RRNA N-glycosylase]]
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[[Category: Betzel C]]
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[[Category: Betzel, C]]
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[[Category: Meyer A]]
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[[Category: Meyer, A]]
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[[Category: Singh TP]]
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[[Category: Singh, T P]]
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[[Category: Weber W]]
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[[Category: Weber, W]]
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[[Category: Hydrolase]]
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[[Category: Irip]]
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[[Category: Pi-loop]]
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[[Category: Ribosome inactivating protein type i]]
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Current revision

Native structure of IRIP, a type I ribosome inactivating protein from Iris hollandica var. at 1.25 A

PDB ID 3mvg

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OCA

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