Ribosome biogenesis protein
From Proteopedia
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== Function == | == Function == | ||
| - | '''Ribosome biogenesis proteins''' are factors which contribute to the maturation of the ribosome. | + | '''Ribosome biogenesis proteins''' or '''ribosome assembly factor''' are factors which contribute to the maturation of the ribosome. |
'''Interactive 3D figure''' on right side shows: Ribosome biogenesis protein Nop10 (pink) complexed with pseudouridine synthase (grey), GAR1 (green), ribosomal protein L7AE (yellow), H/ACA RNA (magenta) and RNA containing pseudouridine (cyan) (PDB code [[3hay]]) | '''Interactive 3D figure''' on right side shows: Ribosome biogenesis protein Nop10 (pink) complexed with pseudouridine synthase (grey), GAR1 (green), ribosomal protein L7AE (yellow), H/ACA RNA (magenta) and RNA containing pseudouridine (cyan) (PDB code [[3hay]]) | ||
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</StructureSection> | </StructureSection> | ||
== 3D Structures of ribosome biogenesis protein == | == 3D Structures of ribosome biogenesis protein == | ||
| - | + | [[Ribosome biogenesis protein 3D structures]] | |
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Ribosome biogenesis protein | ||
| - | |||
| - | **[[6n31]] – hWdr12 residues 90-422 – human <br /> | ||
| - | **[[6p0q]] – hWdr12 ubiquitin-like domain 1-87 <br /> | ||
| - | **[[4u7a]] – yErb1 – yeast <br /> | ||
| - | **[[5iw7]], [[5wwn]] – yTsr1 <br /> | ||
| - | **[[1y2y]] – yNop10 - NMR<br /> | ||
| - | **[[5t9p]] – yNop15 <br /> | ||
| - | **[[5sui]], [[5sum]], [[6en7]] – yNsa1 <br /> | ||
| - | **[[5ydu]] – yUtp30 <br /> | ||
| - | **[[5dtc]] – yYtm1 <br /> | ||
| - | **[[2aqc]] – MjNop10 – ''Methanocaldococcus jannaschii'' - NMR<br /> | ||
| - | **[[3bbe]] – MjNep1 <br /> | ||
| - | |||
| - | *Ribosome biogenesis protein complex | ||
| - | |||
| - | **[[6g18]], [[6g4s]], [[6g4w]], [[6g51]], [[6g53]] – hTsr1 in 40S subunit – Cryo EM<br /> | ||
| - | **[[6zmt]], [[6zn6]] – hTsr1 in 40S subunit + RACK1 + SARS non-structural protein – Cryo EM<br /> | ||
| - | **[[6eml]], [[6fai]], [[6wdr]], [[6y7c]], [[6rbd]] – yTsr1 + 40S ribosome - Cryo EM <br /> | ||
| - | **[[5tzs]], [[5wyj]], [[5wyk]] – yBms1 + 40S ribosome - Cryo EM <br /> | ||
| - | **[[5wxl]], [[5a53]] – yRpf2 + regulator of ribosome biosynthesis <br /> | ||
| - | **[[4clq]] – yBms1 + Rcl1P <br /> | ||
| - | **[[5z1g]] – yBrx1 + EBP2 <br /> | ||
| - | **[[4wjv]] – yNsa2 + ribosome assembly protein 4 + MBP<br /> | ||
| - | **[[5z3g]] – yNop53 + 60S ribosome - Cryo EM <br /> | ||
| - | **[[5ooq]] – yNop53 + ATP-dependent RNA helicase Dob1 <br /> | ||
| - | **[[5ydt]] – yUtp30 + RNA – Cryo EM<br /> | ||
| - | **[[4clq]] – yBms1 + Rcl1P <br /> | ||
| - | **[[6cb1]], [[6em4]], [[6em5]], [[6em3]], [[6c0f]], [[6elz]], [[6em1]], [[5z3g]] – yNsa1 + 60S ribosome - Cryo EM <br /> | ||
| - | **[[5ydt]] – yUtp30 + RNA – Cryo EM<br /> | ||
| - | **[[5cxb]], [[5cxc]], [[5cyk]], [[5em2]] – CtYtm1 + Erb1 C-terminal – ''Chaetomium thermophilum''<br /> | ||
| - | **[[6qtb]] – CtYtm1 + midasin<br /> | ||
| - | **[[3bbh]] – MjNep1 + sinefungin<br /> | ||
| - | **[[3bbd]] – MjNep1 + SAH<br /> | ||
| - | **[[2apo]] – MjNop10 + pseudouridine synthase <br /> | ||
| - | **[[6ppk]] – Tsr1 in 50S subunit – ''Bacillus subtilis'' - Cryo EM<br /> | ||
| - | **[[2aus]] – Nop10 + pseudouridine synthase – ''Pyrococcus abyssi'' <br /> | ||
| - | **[[2ey4]] – PfNop10 + pseudouridine synthase + GAR1 – ''Pyrococcus furiosus'' <br /> | ||
| - | **[[3hjy]] – PfNop10 + pseudouridine synthase + RNA <br /> | ||
| - | **[[2rfk]], [[3mqk]] – PfNop10 + pseudouridine synthase + RNA + GAR1<br /> | ||
| - | **[[2hvy]], [[3hay]] – PfNop10 + pseudouridine synthase + RNA + GAR1 + ribosomal protein L7AE<br /> | ||
| - | **[[3hjw]], [[3lwo]], [[3lwq]], [[3lwr]], [[3lwv]], [[3lwp]], [[3hax]] – PfNop10 + pseudouridine synthase + RNA + ribosomal protein L7AE<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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3D Structures of ribosome biogenesis protein
Ribosome biogenesis protein 3D structures Updated on 02-March-2022
References
- ↑ Marcin W, Neira JL, Bravo J. The Carboxy-Terminal Domain of Erb1 Is a Seven-Bladed ss-Propeller that Binds RNA. PLoS One. 2015 Apr 16;10(4):e0123463. doi: 10.1371/journal.pone.0123463., eCollection 2015. PMID:25880847 doi:http://dx.doi.org/10.1371/journal.pone.0123463
- ↑ Hamma T, Reichow SL, Varani G, Ferre-D'Amare AR. The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs. Nat Struct Mol Biol. 2005 Dec;12(12):1101-7. Epub 2005 Nov 15. PMID:16286935 doi:10.1038/nsmb1036
- ↑ Hu J, Zhu X, Ye K. Structure and RNA recognition of ribosome assembly factor Utp30. RNA. 2017 Sep 26. pii: rna.062695.117. doi: 10.1261/rna.062695.117. PMID:28951391 doi:http://dx.doi.org/10.1261/rna.062695.117
- ↑ McCaughan UM, Jayachandran U, Shchepachev V, Chen ZA, Rappsilber J, Tollervey D, Cook AG. Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases. Nat Commun. 2016 Jun 2;7:11789. doi: 10.1038/ncomms11789. PMID:27250689 doi:http://dx.doi.org/10.1038/ncomms11789
- ↑ Taylor AB, Meyer B, Leal BZ, Kotter P, Schirf V, Demeler B, Hart PJ, Entian KD, Wohnert J. The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site. Nucleic Acids Res. 2008 Mar;36(5):1542-54. Epub 2008 Jan 21. PMID:18208838 doi:10.1093/nar/gkm1172
- ↑ Delprato A, Al Kadri Y, Perebaskine N, Monfoulet C, Henry Y, Henras AK, Fribourg S. Crucial role of the Rcl1p-Bms1p interaction for yeast pre-ribosomal RNA processing. Nucleic Acids Res. 2014;42(15):10161-72. doi: 10.1093/nar/gku682. Epub 2014 Jul, 26. PMID:25064857 doi:http://dx.doi.org/10.1093/nar/gku682
- ↑ Liang B, Zhou J, Kahen E, Terns RM, Terns MP, Li H. Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA. Nat Struct Mol Biol. 2009 Jul;16(7):740-6. Epub 2009 May 28. PMID:19478803 doi:10.1038/nsmb.1624
