7a4i

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'''Unreleased structure'''
 
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The entry 7a4i is ON HOLD until Paper Publication
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==Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-3==
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<StructureSection load='7a4i' size='340' side='right'caption='[[7a4i]], [[Resolution|resolution]] 7.04&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7a4i]] is a 240 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5] and [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A4I FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.04&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a4i OCA], [https://pdbe.org/7a4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a4i RCSB], [https://www.ebi.ac.uk/pdbsum/7a4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a4i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/REGN_LAMBD REGN_LAMBD] Antitermination proteins positively regulate expression of the phage early and late gene operons. Bacterial host RNA polymerase modified by these antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes. N protein regulates the transition from the early to the middle stage of lytic development. It is a transcription antitermination protein that prevents termination at the rho-dependent tL and tR transcription termination sites.[https://www.uniprot.org/uniprot/RISB_AQUAE RISB_AQUAE] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<ref>PMID:12603336</ref> <ref>PMID:11237620</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Escherichia virus Lambda]]
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[[Category: Large Structures]]
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[[Category: Hilvert D]]
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[[Category: Tetter S]]

Current revision

Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-3

PDB ID 7a4i

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