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6an6

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Current revision (13:11, 30 August 2023) (edit) (undo)
 
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<StructureSection load='6an6' size='340' side='right'caption='[[6an6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='6an6' size='340' side='right'caption='[[6an6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6an6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AN6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6AN6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6an6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AN6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J1I:5-S-{2-[{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}(phosphonomethyl)amino]ethyl}-5-thioadenosine'>J1I</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J1I:5-S-{2-[{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}(phosphonomethyl)amino]ethyl}-5-thioadenosine'>J1I</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6an6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6an6 OCA], [http://pdbe.org/6an6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6an6 RCSB], [http://www.ebi.ac.uk/pdbsum/6an6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6an6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6an6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6an6 OCA], [https://pdbe.org/6an6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6an6 RCSB], [https://www.ebi.ac.uk/pdbsum/6an6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6an6 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HPPK_ECOLI HPPK_ECOLI]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ji, X]]
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[[Category: Ji X]]
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[[Category: Shaw, G X]]
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[[Category: Shaw GX]]
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[[Category: Shi, G]]
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[[Category: Shi G]]
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[[Category: Alpha beta]]
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[[Category: Transferase-inhibitor complex]]
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Current revision

Crystal structure of Escherichia coli HPPK in complex with bisubstrate analogue inhibitor HP-72

PDB ID 6an6

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