6awh

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Current revision (14:18, 13 March 2024) (edit) (undo)
 
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<StructureSection load='6awh' size='340' side='right'caption='[[6awh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='6awh' size='340' side='right'caption='[[6awh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6awh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AWH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6AWH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6awh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AWH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=N7G:(2R)-2-hydroxy-N-{3-[(5-methoxypentyl)amino]-3-oxopropyl}-3,3-dimethylbutanamide'>N7G</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=N7G:(2R)-2-hydroxy-N-{3-[(5-methoxypentyl)amino]-3-oxopropyl}-3,3-dimethylbutanamide'>N7G</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6awh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6awh OCA], [http://pdbe.org/6awh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6awh RCSB], [http://www.ebi.ac.uk/pdbsum/6awh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6awh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6awh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6awh OCA], [https://pdbe.org/6awh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6awh RCSB], [https://www.ebi.ac.uk/pdbsum/6awh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6awh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0D6HHM8_STAAU A0A0D6HHM8_STAAU]] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.[HAMAP-Rule:MF_01273]
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[https://www.uniprot.org/uniprot/COAW_STAA8 COAW_STAA8] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.<ref>PMID:12760898</ref>
==See Also==
==See Also==
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pantothenate kinase]]
 
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[[Category: Antoshchenko, T]]
 
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[[Category: Barnard, L]]
 
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[[Category: Chen, Y]]
 
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[[Category: Huang, Y H]]
 
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[[Category: Strauss, E]]
 
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[[Category: Atp]]
 
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[[Category: Pantothenate analog]]
 
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[[Category: Sapank]]
 
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Transferase]]
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[[Category: Antoshchenko T]]
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[[Category: Barnard L]]
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[[Category: Chen Y]]
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[[Category: Huang YH]]
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[[Category: Strauss E]]

Current revision

Staphylococcus aureus Type II pantothenate kinase in complex with ATP and pantothenate analog Deoxy-MeO-N5Pan

PDB ID 6awh

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