This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6axp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:28, 4 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6axp' size='340' side='right'caption='[[6axp]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
<StructureSection load='6axp' size='340' side='right'caption='[[6axp]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6axp]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AXP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6AXP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6axp]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AXP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.484&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=011:7-AMINOHEPTANOIC+ACID'>011</scene>, <scene name='pdbligand=C1J:'>C1J</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=011:7-AMINOHEPTANOIC+ACID'>011</scene>, <scene name='pdbligand=C1J:N~5~-(N-octylcarbamimidoyl)-L-ornithine'>C1J</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ido|5ido]], [[6au5|6au5]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6axp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6axp OCA], [https://pdbe.org/6axp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6axp RCSB], [https://www.ebi.ac.uk/pdbsum/6axp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6axp ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6axp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6axp OCA], [http://pdbe.org/6axp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6axp RCSB], [http://www.ebi.ac.uk/pdbsum/6axp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6axp ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Bzymek, K P]]
+
[[Category: Synthetic construct]]
-
[[Category: Williams, J C]]
+
[[Category: Bzymek KP]]
-
[[Category: Anti-egfr]]
+
[[Category: Williams JC]]
-
[[Category: Antibody]]
+
-
[[Category: Immune system]]
+

Current revision

Structure of cetuximab with aminoheptanoic acid-linked n-octylarginine meditope variant

PDB ID 6axp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6axp"
Personal tools