6irl

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<StructureSection load='6irl' size='340' side='right'caption='[[6irl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='6irl' size='340' side='right'caption='[[6irl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6irl]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6IRL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6irl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Chicken/Hong_Kong/715.5/01_(H5N1)) Influenza A virus (A/Chicken/Hong Kong/715.5/01 (H5N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IRL FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK]), B2M ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6irl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6irl OCA], [http://pdbe.org/6irl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6irl RCSB], [http://www.ebi.ac.uk/pdbsum/6irl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6irl ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6irl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6irl OCA], [https://pdbe.org/6irl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6irl RCSB], [https://www.ebi.ac.uk/pdbsum/6irl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6irl ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/PA_I01A3 PA_I01A3]] Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.[HAMAP-Rule:MF_04063] [[http://www.uniprot.org/uniprot/B2MG_CHICK B2MG_CHICK]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
 
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC I 3D structures|MHC I 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Xiao, L]]
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[[Category: Xiao L]]
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[[Category: Zhang, L]]
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[[Category: Zhang L]]
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[[Category: 8-mer]]
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[[Category: Avian influenza virus]]
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[[Category: Chicken]]
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[[Category: Epitope]]
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[[Category: H5n1]]
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[[Category: Immune system]]
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[[Category: Mhc class i]]
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Current revision

Crystal structure of 8-mer peptide from avian influenza H5N1 virus in complex with BF2*1501

PDB ID 6irl

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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