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2wlj

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Current revision (16:01, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2wlj' size='340' side='right'caption='[[2wlj]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2wlj' size='340' side='right'caption='[[2wlj]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wlj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WLJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wlj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xl4|1xl4]], [[2wln|2wln]], [[2wlo|2wlo]], [[2wll|2wll]], [[2wli|2wli]], [[2wlm|2wlm]], [[1xl6|1xl6]], [[2wlh|2wlh]], [[2wlk|2wlk]], [[2x6b|2x6b]], [[2x6a|2x6a]], [[2x6c|2x6c]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlj OCA], [http://pdbe.org/2wlj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlj RCSB], [http://www.ebi.ac.uk/pdbsum/2wlj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlj OCA], [https://pdbe.org/2wlj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlj RCSB], [https://www.ebi.ac.uk/pdbsum/2wlj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlj ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 31632]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Caputo, A T]]
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[[Category: Magnetospirillum magnetotacticum]]
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[[Category: Clarke, O B]]
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[[Category: Caputo AT]]
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[[Category: Gulbis, J M]]
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[[Category: Clarke OB]]
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[[Category: Smith, B J]]
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[[Category: Gulbis JM]]
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[[Category: Metal transport]]
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[[Category: Smith BJ]]

Current revision

Potassium channel from Magnetospirillum magnetotacticum

PDB ID 2wlj

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