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Sm-like protein

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'''Sm-like proteins''' are ring-shaped oligomers of 6-7 members which show nucleic acid-binding activity<ref>PMID:15009882</ref>. In eukaryotes 7 sm-like proteins (LSm2p-LSm8p) are associated with U6 snRNA<ref>PMID:10747033</ref>. For details on Sm1 of ''Archaeoglobus fulgidus'' see [[AF-Sm1]]. For details on the human protein see [[Lsm]].
'''Sm-like proteins''' are ring-shaped oligomers of 6-7 members which show nucleic acid-binding activity<ref>PMID:15009882</ref>. In eukaryotes 7 sm-like proteins (LSm2p-LSm8p) are associated with U6 snRNA<ref>PMID:10747033</ref>. For details on Sm1 of ''Archaeoglobus fulgidus'' see [[AF-Sm1]]. For details on the human protein see [[Lsm]].
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</StructureSection>
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== 3D Structures of Sm-like protein ==
== 3D Structures of Sm-like protein ==
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[[Sm-like protein 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Sm-like protein
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**[[6vax]] – hLSm10 + LSm11 in histone pre-mRNA machinery – Cryo EM<br />
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**[[2fb7]] – zLSm14 – zebra fish – NMR<br />
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**[[2vxf]] - zLSm14 (mutant) – NMR<br />
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**[[3bw1]] – yLSm3 - yeast<br />
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**[[4n0a]] – yLSm2 + LSm3 + DNA topoisomerase 2-associated protein <br />
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**[[1i81]], [[1jri]], [[1mgq]], [[1jbm]] – MtSm – ''Methanothermobacter thermautotrophicus''<br />
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**[[1loj]] – MtSm + UMP<br />
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**[[1i8f]], [[1m5q]], [[1lnx]] – Sm – ''Pyrobaculum aerophilum''<br />
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**[[1i4k]] – AfSm1 – ''Archaeoglobus fulgidus''<br />
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**[[1i5l]] – AfSm1 + RNA<br />
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**[[1ljo]] – AfSm2<br />
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**[[1m8v]] – PaSm1 + RNA – ''Pyrococcus abyssii''<br />
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**[[1h64]] – PaSm<br />
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**[[3pgg]] – LSm5 – ''Cryptosporidium parvum''<br />
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**[[5mki]], [[5mkn]] – LSm – ''Methanococcus vannielii''<br />
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**[[4xq3]] – LSm – ''Sulfolobus solfataricus''<br />
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**[[5mkl]] – LSm – ''Sulfolobus acidocaldarius''<br />
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*Sm-like protein in spliceosome
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**[[4wzj]], [[5gam]], [[5gao]] – hLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 in spliceosome - human<br />
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**[[6ahd]], [[6ah0]], [[6qw6]], [[3jcr]], [[6qx9]], [[5o9z]], [[6id1]], [[6id0]], [[6icz]], [[5z58]], [[5z57]], [[5z56]], [[5mqf]], [[6fft]], [[5xjc]], [[5yzg]], [[7a5p]], [[6qdv]] – hLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 in spliceosome – Cryo EM<br />
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**[[4c8q]] – yLSm1 + LSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + DNA topoisomerase 2-associated protein <br />
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**[[4c92]], [[4m75]] – yLSm1 + LSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 <br />
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**[[4c8q]] – yLSm1 + LSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + DNA topoisomerase 2-associated protein <br />
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**[[4m77]], [[4m78]] – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 <br />
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**[[5zwo]], [[5zwn]], [[5zwm]], [[6g90]], [[3jcm]], [[5gan]], [[5nrl]], [[5lj3]], [[6n7p]], [[5lqw]], [[5lj5]], [[5mps]], [[5mq0]], [[5gmk]], [[6j6g]], [[6j6h]], [[5ylz]], [[6j6q]], [[6j6n]], [[5wsg]], [[6bk8]], [[6exn]], [[5y88]], [[5gm6]] – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 in spliceosome – Cryo EM<br />
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**[[4m7a]] – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 + U6 SnRNA<br />
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**[[5vsu]], [[6aso]] – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 + U6 SnRNA + RNA<br />
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**[[4m7d]] – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 + RNA<br />
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**[[3swn]], [[4emk]] – fyLSm5 + LSm6 + LSm7 – fission yeast<br />
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**[[6ppn]], [[6ppp]] – fyLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 + U6 snRNA<br />
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**[[6ppv]], [[6ppq]] – fyLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 + RNA<br />
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**[[3jb9]] – fyLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 in spliceosome – Cryo EM<br />
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}}
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== References ==
== References ==
<references/>
<references/>
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</StructureSection>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Sm1 7-member ring dimer complex with RNA, UMP and Ca+2 (green) ions 1m8v

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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