6blb

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Current revision (14:44, 4 October 2023) (edit) (undo)
 
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<StructureSection load='6blb' size='340' side='right'caption='[[6blb]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='6blb' size='340' side='right'caption='[[6blb]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6blb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BLB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6BLB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6blb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BLB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6blb OCA], [http://pdbe.org/6blb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6blb RCSB], [http://www.ebi.ac.uk/pdbsum/6blb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6blb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6blb OCA], [https://pdbe.org/6blb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6blb RCSB], [https://www.ebi.ac.uk/pdbsum/6blb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6blb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RUVB_PSEAE RUVB_PSEAE]] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.[HAMAP-Rule:MF_00016]
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[https://www.uniprot.org/uniprot/RUVB_PSEAE RUVB_PSEAE] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.[HAMAP-Rule:MF_00016]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA helicase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, W F]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Structural genomic]]
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[[Category: Anderson WF]]
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[[Category: Dubrovska, I]]
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[[Category: Dubrovska I]]
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[[Category: Grimshaw, S]]
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[[Category: Grimshaw S]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Kiryukhina, O]]
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[[Category: Kiryukhina O]]
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[[Category: Kwon, K]]
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[[Category: Kwon K]]
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[[Category: Minasov, G]]
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[[Category: Minasov G]]
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[[Category: Satchell, K J.F]]
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[[Category: Satchell KJF]]
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[[Category: Shuvalova, L]]
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[[Category: Shuvalova L]]
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[[Category: Adp]]
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[[Category: Csgid]]
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[[Category: Holliday junction atp-dependent dna helicase]]
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[[Category: Hydrolase]]
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Current revision

1.88 Angstrom Resolution Crystal Structure Holliday Junction ATP-dependent DNA Helicase (RuvB) from Pseudomonas aeruginosa in Complex with ADP

PDB ID 6blb

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