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6c79

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Current revision (14:26, 13 March 2024) (edit) (undo)
 
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<StructureSection load='6c79' size='340' side='right'caption='[[6c79]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
<StructureSection load='6c79' size='340' side='right'caption='[[6c79]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6c79]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C79 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6C79 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6c79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C79 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c79 OCA], [https://pdbe.org/6c79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c79 RCSB], [https://www.ebi.ac.uk/pdbsum/6c79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c79 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6c79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c79 OCA], [http://pdbe.org/6c79 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c79 RCSB], [http://www.ebi.ac.uk/pdbsum/6c79 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c79 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX]] Has strong cefotaxime-hydrolyzing activity.
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[https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Coates, L]]
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[[Category: Coates L]]
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[[Category: Cooper, S J]]
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[[Category: Cooper SJ]]
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[[Category: Ginell, S L]]
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[[Category: Ginell SL]]
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[[Category: Langan, P S]]
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[[Category: Langan PS]]
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[[Category: Parks, J M]]
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[[Category: Parks JM]]
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[[Category: Vandavasi, V G]]
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[[Category: Vandavasi VG]]
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[[Category: Weiss, K L]]
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[[Category: Weiss KL]]
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[[Category: Hydrolase]]
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Current revision

Conformational Changes in a Class A Beta lactamase that Prime it for Catalysis

PDB ID 6c79

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