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1d29

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[[Image:1d29.gif|left|200px]]
 
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==CRYSTAL STRUCTURE ANALYSIS OF THE B-DNA DODECAMER CGTGAATTCACG==
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The line below this paragraph, containing "STRUCTURE_1d29", creates the "Structure Box" on the page.
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<StructureSection load='1d29' size='340' side='right'caption='[[1d29]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1d29]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D29 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d29 OCA], [https://pdbe.org/1d29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d29 RCSB], [https://www.ebi.ac.uk/pdbsum/1d29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d29 ProSAT]</span></td></tr>
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{{STRUCTURE_1d29| PDB=1d29 | SCENE= }}
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</table>
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__TOC__
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'''CRYSTAL STRUCTURE ANALYSIS OF THE B-DNA DODECAMER CGTGAATTCACG'''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Dickerson RE]]
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==Overview==
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[[Category: Kopka ML]]
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The crystal structure of the DNA dodecamer C-G-T-G-A-A-T-T-C-A-C-G has been determined at a resolution of 2.5 A, with a final R factor of 15.8% for 1475 nonzero reflections measured at 0 degrees C. The structure is isomorphous with that of the Drew dodecamer, with the space group P2(1)2(1)2(1) and cell dimensions of a = 24.94 A, b = 40.78 A, and c = 66.13 A. The asymmetric unit contains all 12 base pairs of the B-DNA double helix and 36 water molecules. The structure of C-G-T-G-A-A-T-T-C-A-C-G is very similar to that of C-G-C-G-A-A-T-T-C-G-C-G, with no major alterations in helix parameters. Water peaks in the refined structure appear to represent a selection of peaks that were observed in the Drew dodecamer. The minor-groove spine of hydration at 2.5 A is fragmentary, but as Narendra et al. (1991) [Biochemistry (following paper in this issue)] have observed, lowering the temperature leads to a more complete representation of the spine.
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[[Category: Larsen TA]]
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==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D29 OCA].
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==Reference==
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Crystal structure analysis of the B-DNA dodecamer CGTGAATTCACG., Larsen TA, Kopka ML, Dickerson RE, Biochemistry. 1991 May 7;30(18):4443-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1850624 1850624]
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[[Category: Dickerson, R E.]]
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[[Category: Kopka, M L.]]
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[[Category: Larsen, T A.]]
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[[Category: B-dna]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:22:02 2008''
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Current revision

CRYSTAL STRUCTURE ANALYSIS OF THE B-DNA DODECAMER CGTGAATTCACG

PDB ID 1d29

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