This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7ko6
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7ko6 is ON HOLD Authors: Description: Category: Unreleased Structures) |
|||
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==C1B domain of Protein kinase C in complex with ingenol-3-angelate and phosphocholine== | |
| + | <StructureSection load='7ko6' size='340' side='right'caption='[[7ko6]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ko6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KO6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WUD:ingenol-3-angelate'>WUD</scene>, <scene name='pdbligand=XP5:(4S,7R)-7-(HEPTANOYLOXY)-4-HYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEXADECAN-1-AMINIUM+4-OXIDE'>XP5</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ko6 OCA], [https://pdbe.org/7ko6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ko6 RCSB], [https://www.ebi.ac.uk/pdbsum/7ko6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ko6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A140UHX0_RAT A0A140UHX0_RAT] Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.[PIRNR:PIRNR000551] | ||
| - | + | ==See Also== | |
| - | + | *[[Protein kinase C 3D structures|Protein kinase C 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Katti SS]] | ||
| + | [[Category: Krieger IV]] | ||
Current revision
C1B domain of Protein kinase C in complex with ingenol-3-angelate and phosphocholine
| |||||||||||
