7kpp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7kpp is ON HOLD Authors: Czub, M.P., Porebski, P.J., Majorek, K.A., Cymborowski, M., Minor, W., Center for Structural Genomics of Infectious Disease...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the E102A mutant of a GNAT superfamily PA3944 acetyltransferase== | |
| + | <StructureSection load='7kpp' size='340' side='right'caption='[[7kpp]], [[Resolution|resolution]] 1.45Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7kpp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KPP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kpp OCA], [https://pdbe.org/7kpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kpp RCSB], [https://www.ebi.ac.uk/pdbsum/7kpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kpp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ATSE3_PSEAE ATSE3_PSEAE] Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers the peptide Asp-Phe methyl ester (or aspartame) and the peptide antibiotics polymyxin B and colistin. Other substrates like dopamine, serotonin, puromycin, chloramphenicol, D-glucosamine, glycine and N-alpha-acetyl-L-glutamine are used and displayed lower activity.<ref>PMID:23184347</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Nonstructural protein 3D structures|Nonstructural protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa]] |
| - | [[Category: | + | [[Category: Cymborowski M]] |
| - | [[Category: | + | [[Category: Czub MP]] |
| + | [[Category: Majorek KA]] | ||
| + | [[Category: Minor W]] | ||
| + | [[Category: Porebski PJ]] | ||
Current revision
Structure of the E102A mutant of a GNAT superfamily PA3944 acetyltransferase
| |||||||||||
