This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7kps
From Proteopedia
(Difference between revisions)
m (Protected "7kps" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a GNAT superfamily PA3944 acetyltransferase in complex with AcCoA== | |
| - | + | <StructureSection load='7kps' size='340' side='right'caption='[[7kps]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7kps]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KPS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kps OCA], [https://pdbe.org/7kps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kps RCSB], [https://www.ebi.ac.uk/pdbsum/7kps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kps ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/ATSE3_PSEAE ATSE3_PSEAE] Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers the peptide Asp-Phe methyl ester (or aspartame) and the peptide antibiotics polymyxin B and colistin. Other substrates like dopamine, serotonin, puromycin, chloramphenicol, D-glucosamine, glycine and N-alpha-acetyl-L-glutamine are used and displayed lower activity.<ref>PMID:23184347</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa]] | ||
| + | [[Category: Becker DP]] | ||
| + | [[Category: Cymborowski M]] | ||
| + | [[Category: Czub MP]] | ||
| + | [[Category: Minor W]] | ||
| + | [[Category: Porebski PJ]] | ||
| + | [[Category: Reidl CT]] | ||
Current revision
Structure of a GNAT superfamily PA3944 acetyltransferase in complex with AcCoA
| |||||||||||
