6t35

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==Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101)==
==Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101)==
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<StructureSection load='6t35' size='340' side='right'caption='[[6t35]]' scene=''>
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<StructureSection load='6t35' size='340' side='right'caption='[[6t35]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T35 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6T35 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6t35]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T35 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6t35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t35 OCA], [http://pdbe.org/6t35 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6t35 RCSB], [http://www.ebi.ac.uk/pdbsum/6t35 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6t35 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=M9W:Enmetazobactam+derived+trans-enamine+adduct.'>M9W</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t35 OCA], [https://pdbe.org/6t35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t35 RCSB], [https://www.ebi.ac.uk/pdbsum/6t35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t35 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Brem J]]
[[Category: Brem J]]

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Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101)

PDB ID 6t35

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