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7bx7

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==Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain==
==Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain==
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<StructureSection load='7bx7' size='340' side='right'caption='[[7bx7]]' scene=''>
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<StructureSection load='7bx7' size='340' side='right'caption='[[7bx7]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BX7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7BX7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7bx7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BX7 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7bx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bx7 OCA], [http://pdbe.org/7bx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7bx7 RCSB], [http://www.ebi.ac.uk/pdbsum/7bx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7bx7 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bx7 OCA], [https://pdbe.org/7bx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bx7 RCSB], [https://www.ebi.ac.uk/pdbsum/7bx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bx7 ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>
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==See Also==
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*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Li D]]
[[Category: Li D]]

Current revision

Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain

PDB ID 7bx7

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