1h80

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<StructureSection load='1h80' size='340' side='right'caption='[[1h80]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1h80' size='340' side='right'caption='[[1h80]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1h80]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Altfo Altfo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H80 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1H80 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1h80]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alteromonas_macleodii Alteromonas macleodii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H80 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ktw|1ktw]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CGIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=116059 ALTFO])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h80 OCA], [https://pdbe.org/1h80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h80 RCSB], [https://www.ebi.ac.uk/pdbsum/1h80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h80 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Iota-carrageenase Iota-carrageenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.157 3.2.1.157] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1h80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h80 OCA], [http://pdbe.org/1h80 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h80 RCSB], [http://www.ebi.ac.uk/pdbsum/1h80 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1h80 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/CGIA_ALTFO CGIA_ALTFO]] Hydrolyzes iota-carrageenans, sulfated 1,3-alpha-1,4-beta galactans from red algal cell walls, with an inversion of anomeric configuration. Also active against hybrid iota-/nu-carrageenan, not active against kappa- or lambda-carrageenans.<ref>PMID:10934194</ref> <ref>PMID:20227066</ref> [UniProtKB:Q9F284]
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/1h80_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/1h80_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Altfo]]
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[[Category: Alteromonas macleodii]]
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[[Category: Iota-carrageenase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chantalat, L]]
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[[Category: Chantalat L]]
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[[Category: Dideberg, O]]
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[[Category: Dideberg O]]
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[[Category: Michel, G]]
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[[Category: Michel G]]
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[[Category: Hydrolase]]
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[[Category: Iota-carrageenan double helix degradation]]
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Current revision

1,3-ALPHA-1,4-BETA-D-GALACTOSE-4-SULFATE- 3,6-ANHYDRO-D-GALACTOSE-2-SULFATE 4 GALACTOHYDROLASE

PDB ID 1h80

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