This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1jwo
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='1jwo' size='340' side='right'caption='[[1jwo]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='1jwo' size='340' side='right'caption='[[1jwo]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1jwo]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1jwo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JWO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JWO FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jwo OCA], [https://pdbe.org/1jwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jwo RCSB], [https://www.ebi.ac.uk/pdbsum/1jwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jwo ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MATK_HUMAN MATK_HUMAN] Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.<ref>PMID:9171348</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 24: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Murthy TVS]] | |
| - | [[Category: Murthy | + | [[Category: Webster GD]] |
| - | [[Category: Webster | + | |
| - | + | ||
Current revision
Crystal Structure Analysis of the SH2 Domain of the Csk Homologous Kinase CHK
| |||||||||||
