7jlx
From Proteopedia
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==Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ (TIR domains)== | ==Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ (TIR domains)== | ||
| - | <StructureSection load='7jlx' size='340' side='right'caption='[[7jlx]]' scene=''> | + | <StructureSection load='7jlx' size='340' side='right'caption='[[7jlx]], [[Resolution|resolution]] 4.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JLX OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[7jlx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_benthamiana Nicotiana benthamiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JLX FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.6Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jlx OCA], [https://pdbe.org/7jlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jlx RCSB], [https://www.ebi.ac.uk/pdbsum/7jlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jlx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ROQ1_NICBE ROQ1_NICBE] Disease resistance (R) protein that specifically recognizes the Xanthomonas and Pseudomonas effector proteins XopQ and HopQ1, and triggers cell death (PubMed:28891100). Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792).<ref>PMID:28891100</ref> <ref>PMID:31439792</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Nicotiana benthamiana]] | ||
[[Category: King M]] | [[Category: King M]] | ||
[[Category: Lui F]] | [[Category: Lui F]] | ||
Current revision
Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ (TIR domains)
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Categories: Large Structures | Nicotiana benthamiana | King M | Lui F | Martin R | Nogales E | Qi T | Staskawicz BJ | Toth C | Zhang H
