6tbw

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<StructureSection load='6tbw' size='340' side='right'caption='[[6tbw]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
<StructureSection load='6tbw' size='340' side='right'caption='[[6tbw]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6tbw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TBW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TBW FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TBW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ampC, ampA, b4150, JW4111 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tbw OCA], [https://pdbe.org/6tbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tbw RCSB], [https://www.ebi.ac.uk/pdbsum/6tbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tbw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tbw OCA], [http://pdbe.org/6tbw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tbw RCSB], [http://www.ebi.ac.uk/pdbsum/6tbw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tbw ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI]] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
 
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[[Category: Ecoli]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Brem, J]]
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[[Category: Brem J]]
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[[Category: Lang, P A]]
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[[Category: Lang PA]]
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[[Category: Leissing, T M]]
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[[Category: Leissing TM]]
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[[Category: Schofield, C J]]
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[[Category: Schofield CJ]]
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[[Category: Antibiotic resistance]]
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[[Category: Beta lactamase]]
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[[Category: Dbo]]
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[[Category: Diazabicyclooctane]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of AmpC from E.coli with Avibactam

PDB ID 6tbw

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