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Toll-like Receptor 3D structures
From Proteopedia
(Difference between revisions)
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Toll-like receptor 1; Domains – TIR 625-785; ligand-binding (LBD) 22-703; transmembrane 698-730 | + | *Toll-like receptor 1; Domains – Transmembrane+juxtamembrane 581-629; TIR 625-785; ligand-binding (LBD) 22-703; transmembrane 698-730 |
**[[1fyv]] – hTLR1 TIR domain – human<br /> | **[[1fyv]] – hTLR1 TIR domain – human<br /> | ||
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*Toll-like receptor 2 | *Toll-like receptor 2 | ||
| - | **[[1fyw]] – hTLR2 TIR domain<br /> | + | **[[8ar0]], [[8ar1]], [[8ar2]], [[8ar3]] – hTLR2 transmembrane+juxtamembrane domain – NMR<br /> |
| + | **[[1fyw]], [[7nux]], [[7nux]] – hTLR2 TIR domain<br /> | ||
| + | **[[7nt7]] – hTLR1 TIR domain – NMR<br /> | ||
**[[1fyx]], [[1o77]] - hTLR2 TIR domain (mutant) <br /> | **[[1fyx]], [[1o77]] - hTLR2 TIR domain (mutant) <br /> | ||
**[[2z80]] – hTLR2/VLRB.61<br /> | **[[2z80]] – hTLR2/VLRB.61<br /> | ||
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**[[2mk9]], [[2mka]] – hTLR3 transmembrane domain - NMR <br /> | **[[2mk9]], [[2mka]] – hTLR3 transmembrane domain - NMR <br /> | ||
**[[3ulv]], [[3ulu]], [[5gs0]] – hTLR3 LBD + antibody<br /> | **[[3ulv]], [[3ulu]], [[5gs0]] – hTLR3 LBD + antibody<br /> | ||
| + | **[[7c76]] – hTLR3 + UNC93B1 – Cryo EM<br /> | ||
| + | **[[7wm4]], [[7wv3]], [[7wv4]], [[7wv5]], [[7wvj]] – hTLR3 LBD + RNA – Cryo EM<br /> | ||
| + | **[[7wve]] – hTLR3 LBD (mutant) + RNA – Cryo EM<br /> | ||
| + | **[[7wvf]] – hTLR3 LBD + antibody + RNA – Cryo EM<br /> | ||
| + | **[[7c77]] – mTLR3 + UNC93B1 – Cryo EM<br /> | ||
| + | **[[7da7]], [[7das]] – mTLR3 LBD + RNA – Cryo EM<br /> | ||
**[[3cig]] – mTLR3 LBD<br /> | **[[3cig]] – mTLR3 LBD<br /> | ||
**[[3ciy]] - mTLR3 LBD + RNA<br /> | **[[3ciy]] - mTLR3 LBD + RNA<br /> | ||
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**[[3ula]] - hTLR4/VLRB.61 + lymphocyte antigen 96<br /> | **[[3ula]] - hTLR4/VLRB.61 + lymphocyte antigen 96<br /> | ||
**[[2z64]], [[2z65]], [[5ijc]], [[5ijd]], [[3vq1]], [[3vq2]] – mTLR4 LBD + lymphocyte antigen 96<br /> | **[[2z64]], [[2z65]], [[5ijc]], [[5ijd]], [[3vq1]], [[3vq2]] – mTLR4 LBD + lymphocyte antigen 96<br /> | ||
| + | **[[7mlm]] - mTLR4/VLRB.61 + lymphocyte antigen 96 + sulfatide<br /> | ||
*Toll-like receptor 5 | *Toll-like receptor 5 | ||
**[[3j0a]] – hTLR5<br /> | **[[3j0a]] – hTLR5<br /> | ||
| + | |||
| + | *Toll-like receptor 5A | ||
| + | |||
| + | **[[7b1b]], [[7b1c]], [[7b1d]] – TLR5A + Spz1C – yellow fever mosquito - Cryo EM<br /> | ||
*Toll-like receptor 5B | *Toll-like receptor 5B | ||
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*Toll-like receptor 7 | *Toll-like receptor 7 | ||
| + | **[[7cyn]] – hTLR7 + UNC93B1 – Cryo EM<br /> | ||
**[[5gmf]] – moTLR7 + guanosine + poly-U - monkey <br /> | **[[5gmf]] – moTLR7 + guanosine + poly-U - monkey <br /> | ||
**[[5gmg]] – moTLR7 + loxoribine + poly-U <br /> | **[[5gmg]] – moTLR7 + loxoribine + poly-U <br /> | ||
**[[5gmh]] – moTLR7 + resiquimod + poly-U <br /> | **[[5gmh]] – moTLR7 + resiquimod + poly-U <br /> | ||
| + | **[[5zsl]], [[5zsm]], [[5zsn]] – moTLR7 (mutant) + RNA <br /> | ||
| + | **[[5zsg]], [[5zsh]], [[5zsi]], [[5zsj]], [[6lvz]], [[6lw1]], [[7ytp]] – moTLR7 (mutant) + inhibitor<br /> | ||
| + | **[[6lvx]], [[6lvy]], [[6lw0]] – moTLR7 (mutant) + antagonist<br /> | ||
| + | **[[6if5]] – moTLR7 (mutant) + cGMP<br /> | ||
| + | **[[5zsf]] – moTLR7 (mutant) + drug<br /> | ||
| + | **[[5zsa]], [[5zsb]], [[5zsd]], [[5zse]] – moTLR7 (mutant) + RNA + inhibitort<br /> | ||
*Toll-like receptor 8 | *Toll-like receptor 8 | ||
**[[3w3g]], [[5hdh]] – hTLR8 <br /> | **[[3w3g]], [[5hdh]] – hTLR8 <br /> | ||
| - | **[[3w3j]], [[3w3k]], [[3w3l]], [[3w3m]], [[3w3n]], [[3wn4]], [[5awa]], [[5awc]], [[5awb]], [[5awd]], [[4r6a]], [[4qbz]], [[4qc0]], [[5az5]] – hTLR8 + agonist<br /> | + | **[[3w3j]], [[3w3k]], [[3w3l]], [[3w3m]], [[3w3n]], [[3wn4]], [[5awa]], [[5awc]], [[5awb]], [[5awd]], [[4r6a]], [[4qbz]], [[4qc0]], [[5az5]], [[6v9u]], [[6wml]], [[6zjz]], [[7crf]], [[7r52]], [[7r53]], [[7r54]] – hTLR8 + agonist<br /> |
| + | **[[6kya]], [[6ty5]], [[7rc9]], [[7ytx]], [[8pfi]] – hTLR8 + antagonist<br /> | ||
**[[4r07]], [[4r09]] – hTLR8 + ORN06 <br /> | **[[4r07]], [[4r09]] – hTLR8 + ORN06 <br /> | ||
**[[4r08]] – hTLR8 + RNA <br /> | **[[4r08]] – hTLR8 + RNA <br /> | ||
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**[[4z0c]] – mTLR13 + RNA <br /> | **[[4z0c]] – mTLR13 + RNA <br /> | ||
| + | |||
| + | *Toll-like receptor 15 | ||
| + | |||
| + | **[[7ylf]], [[7ylg]] – TLR10 TIR domain - chicken<br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
3D Structures of Toll-like Receptors
Updated on 27-December-2023 - For a general description of the protein see Toll-like Receptors
