7b2l
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7b2l is ON HOLD Authors: Klebl, D.P., Lizarrondo, J., Sobott, F., Garcia-Alai, M., Muench, S.P. Description: Structure of the endocytic adaptor com...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the endocytic adaptor complex AENTH== | |
| + | <StructureSection load='7b2l' size='340' side='right'caption='[[7b2l]], [[Resolution|resolution]] 3.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7b2l]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B2L FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PIO:[(2R)-2-OCTANOYLOXY-3-[OXIDANYL-[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIS(OXIDANYL)-4,5-DIPHOSPHONOOXY-CYCLOHEXYL]OXY-PHOSPHORYL]OXY-PROPYL]+OCTANOATE'>PIO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b2l OCA], [https://pdbe.org/7b2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b2l RCSB], [https://www.ebi.ac.uk/pdbsum/7b2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b2l ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ENT1_YEAST ENT1_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Negatively regulated via phosphorylation.<ref>PMID:10449404</ref> <ref>PMID:11694597</ref> <ref>PMID:12529323</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Epsin|Epsin]] | |
| - | + | == References == | |
| - | [[ | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Garcia-Alai | + | [[Category: Large Structures]] |
| - | [[Category: Klebl | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: Sobott | + | [[Category: Garcia-Alai M]] |
| + | [[Category: Klebl DP]] | ||
| + | [[Category: Lizarrondo J]] | ||
| + | [[Category: Muench SP]] | ||
| + | [[Category: Sobott F]] | ||
Current revision
Structure of the endocytic adaptor complex AENTH
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