7b61
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7b61 is ON HOLD Authors: Koekemoer, L., Steindel, M., Fairhead, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Krojer, T., Structu...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of MurE from E.coli in complex with Z57299526== | |
| + | <StructureSection load='7b61' size='340' side='right'caption='[[7b61]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7b61]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B61 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=SYQ:(S)-N-(1-cyclopropylethyl)-6-methylpicolinamide'>SYQ</scene>, <scene name='pdbligand=T3Z:(R)-N-(1-cyclopropylethyl)-6-methylpicolinamide'>T3Z</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b61 OCA], [https://pdbe.org/7b61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b61 RCSB], [https://www.ebi.ac.uk/pdbsum/7b61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b61 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MURE_ECOLI MURE_ECOLI] Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine.<ref>PMID:2269304</ref> <ref>PMID:3905407</ref> <ref>PMID:11124264</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Mur ligase|Mur ligase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Fairhead | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Douangamath A]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Fairhead M]] |
| + | [[Category: Koekemoer L]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Steindel M]] | ||
| + | [[Category: Talon R]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of MurE from E.coli in complex with Z57299526
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