7jic
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment== | |
| + | <StructureSection load='7jic' size='340' side='right'caption='[[7jic]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7jic]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JIC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jic OCA], [https://pdbe.org/7jic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jic RCSB], [https://www.ebi.ac.uk/pdbsum/7jic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jic ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CD19_HUMAN CD19_HUMAN] Common variable immunodeficiency. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD19_HUMAN CD19_HUMAN] Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. | ||
| - | + | ==See Also== | |
| - | + | *[[CD81|CD81]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Blacklow SC]] | ||
| + | [[Category: Kruse AC]] | ||
| + | [[Category: Rawson S]] | ||
| + | [[Category: Susa KJ]] | ||
Current revision
Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment
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