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7kzp
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the human Fanconi anaemia Core complex== | |
| - | + | <StructureSection load='7kzp' size='340' side='right'caption='[[7kzp]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7kzp]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KZP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kzp OCA], [https://pdbe.org/7kzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kzp RCSB], [https://www.ebi.ac.uk/pdbsum/7kzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kzp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/FANCA_HUMAN FANCA_HUMAN] Fanconi anemia. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FANCA_HUMAN FANCA_HUMAN] DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pavletich NP]] | ||
| + | [[Category: Wang SL]] | ||
Current revision
Structure of the human Fanconi anaemia Core complex
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