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1sbq

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Current revision (08:30, 1 May 2024) (edit) (undo)
 
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<StructureSection load='1sbq' size='340' side='right'caption='[[1sbq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1sbq' size='340' side='right'caption='[[1sbq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1sbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"filterable_agent_of_primary_atypical_pneumonia"_eaton_et_al._1944 "filterable agent of primary atypical pneumonia" eaton et al. 1944]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SBQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1SBQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1sbq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SBQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPN348, MP488 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2104 "Filterable agent of primary atypical pneumonia" Eaton et al. 1944])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-formyltetrahydrofolate_cyclo-ligase 5-formyltetrahydrofolate cyclo-ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.2 6.3.3.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sbq OCA], [https://pdbe.org/1sbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sbq RCSB], [https://www.ebi.ac.uk/pdbsum/1sbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sbq ProSAT], [https://www.topsan.org/Proteins/BSGC/1sbq TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1sbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sbq OCA], [http://pdbe.org/1sbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sbq RCSB], [http://www.ebi.ac.uk/pdbsum/1sbq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sbq ProSAT], [http://www.topsan.org/Proteins/BSGC/1sbq TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MTHFS_MYCPN MTHFS_MYCPN] Involved in folate metabolism. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.<ref>PMID:16104022</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sbq ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sbq ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Filterable agent of primary atypical pneumonia eaton et al. 1944]]
 
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[[Category: 5-formyltetrahydrofolate cyclo-ligase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Mycoplasma pneumoniae]]
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[[Category: Chen, S]]
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[[Category: Chen S]]
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[[Category: Kim, R]]
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[[Category: Kim R]]
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[[Category: Kim, S H]]
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[[Category: Kim SH]]
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[[Category: Pufan, R]]
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[[Category: Pufan R]]
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[[Category: Shin, D H]]
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[[Category: Shin DH]]
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[[Category: 10-methenyltetrahydrofolate synthetase]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Ligase]]
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[[Category: Mthf]]
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[[Category: PSI, Protein structure initiative]]
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Current revision

Crystal Structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae at 2.2 resolution

PDB ID 1sbq

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