7b9w
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of MurE from E.coli in complex with Z757284380== | |
+ | <StructureSection load='7b9w' size='340' side='right'caption='[[7b9w]], [[Resolution|resolution]] 1.82Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[7b9w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B9W FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=T4H:3-Chloro-N-[2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethyl]benzamide'>T4H</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b9w OCA], [https://pdbe.org/7b9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b9w RCSB], [https://www.ebi.ac.uk/pdbsum/7b9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b9w ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MURE_ECOLI MURE_ECOLI] Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine.<ref>PMID:2269304</ref> <ref>PMID:3905407</ref> <ref>PMID:11124264</ref> | ||
- | + | ==See Also== | |
- | + | *[[Mur ligase|Mur ligase]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: Bountra | + | [[Category: Escherichia coli K-12]] |
- | [[Category: Edwards | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Arrowsmith CH]] |
- | [[Category: | + | [[Category: Bountra C]] |
- | [[Category: | + | [[Category: Edwards AM]] |
- | [[Category: | + | [[Category: Fairhead M]] |
- | [[Category: | + | [[Category: Koekemoer L]] |
+ | [[Category: Krojer T]] | ||
+ | [[Category: Steindel M]] | ||
+ | [[Category: Von Delft F]] |
Current revision
Crystal structure of MurE from E.coli in complex with Z757284380
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