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7dp5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mutant V45A Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate== | |
| + | <StructureSection load='7dp5' size='340' side='right'caption='[[7dp5]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7dp5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brugia_malayi Brugia malayi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DP5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dp5 OCA], [https://pdbe.org/7dp5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dp5 RCSB], [https://www.ebi.ac.uk/pdbsum/7dp5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dp5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A4E9EZW9_BRUMA A0A4E9EZW9_BRUMA] | ||
| - | + | ==See Also== | |
| - | + | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Brugia malayi]] |
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Canyuk B]] |
| - | [[Category: | + | [[Category: Chen C-J]] |
| - | [[Category: | + | [[Category: Keyunratsami K]] |
| - | [[Category: | + | [[Category: Nualnoi T]] |
| + | [[Category: Songsiriritthigul C]] | ||
| + | [[Category: Wongkamchai S]] | ||
Current revision
Crystal structure of mutant V45A Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate
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