7dpa
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex== | |
| + | <StructureSection load='7dpa' size='340' side='right'caption='[[7dpa]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7dpa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DPA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dpa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dpa OCA], [https://pdbe.org/7dpa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dpa RCSB], [https://www.ebi.ac.uk/pdbsum/7dpa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dpa ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DOCK5_HUMAN DOCK5_HUMAN] Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).[UniProtKB:B2RY04]<ref>PMID:19004829</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Dedicator of cytokinesis protein 3D structures|Dedicator of cytokinesis protein 3D structures]] | |
| - | + | *[[Rac 3D structures|Rac 3D structures]] | |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ehara H]] | ||
| + | [[Category: Hanada K]] | ||
| + | [[Category: Ikeda M]] | ||
| + | [[Category: Katsura K]] | ||
| + | [[Category: Kaushik R]] | ||
| + | [[Category: Kukimoto-Niino M]] | ||
| + | [[Category: Mishima-Tsumagari C]] | ||
| + | [[Category: Shirouzu M]] | ||
| + | [[Category: Uchikubo-Kamo T]] | ||
| + | [[Category: Yokoyama T]] | ||
| + | [[Category: Yonemochi M]] | ||
| + | [[Category: Zhang KYJ]] | ||
Current revision
Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex
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