7b6k
From Proteopedia
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==Crystal structure of MurE from E.coli in complex with Z57715447== | ==Crystal structure of MurE from E.coli in complex with Z57715447== | ||
| - | <StructureSection load='7b6k' size='340' side='right'caption='[[7b6k]]' scene=''> | + | <StructureSection load='7b6k' size='340' side='right'caption='[[7b6k]], [[Resolution|resolution]] 1.84Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B6K OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[7b6k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B6K FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.838Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=SZ2:5-cyclohexyl-3-(pyridin-4-yl)-1,2,4-oxadiazole'>SZ2</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b6k OCA], [https://pdbe.org/7b6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b6k RCSB], [https://www.ebi.ac.uk/pdbsum/7b6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b6k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MURE_ECOLI MURE_ECOLI] Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine.<ref>PMID:2269304</ref> <ref>PMID:3905407</ref> <ref>PMID:11124264</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Mur ligase|Mur ligase]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | [[Category: Arrowsmith CH]] | ||
[[Category: Bountra C]] | [[Category: Bountra C]] | ||
| + | [[Category: Douangamath A]] | ||
[[Category: Edwards AM]] | [[Category: Edwards AM]] | ||
[[Category: Fairhead M]] | [[Category: Fairhead M]] | ||
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[[Category: Krojer T]] | [[Category: Krojer T]] | ||
[[Category: Steindel M]] | [[Category: Steindel M]] | ||
| + | [[Category: Talon R]] | ||
[[Category: Von Delft F]] | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of MurE from E.coli in complex with Z57715447
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