1t7s

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<StructureSection load='1t7s' size='340' side='right'caption='[[1t7s]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1t7s' size='340' side='right'caption='[[1t7s]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1t7s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7S OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1T7S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1t7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T7S FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hx1|1hx1]], [[1i6z|1i6z]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bag-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t7s OCA], [https://pdbe.org/1t7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t7s RCSB], [https://www.ebi.ac.uk/pdbsum/1t7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t7s ProSAT], [https://www.topsan.org/Proteins/SECSG/1t7s TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1t7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t7s OCA], [http://pdbe.org/1t7s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1t7s RCSB], [http://www.ebi.ac.uk/pdbsum/1t7s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1t7s ProSAT], [http://www.topsan.org/Proteins/SECSG/1t7s TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BAG1_CAEEL BAG1_CAEEL]] May inhibit the chaperone activity of HSP70/HSC70 by promoting substrate release in an ATP-dependent manner (By similarity).
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[https://www.uniprot.org/uniprot/BAG1_CAEEL BAG1_CAEEL] May inhibit the chaperone activity of HSP70/HSC70 by promoting substrate release in an ATP-dependent manner (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t7/1t7s_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t7/1t7s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caeel]]
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[[Category: Caenorhabditis elegans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bunzel, R]]
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[[Category: Bunzel R]]
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[[Category: Li, S]]
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[[Category: Li S]]
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[[Category: Luan, C H]]
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[[Category: Luan C-H]]
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[[Category: Luo, M]]
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[[Category: Luo M]]
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[[Category: Pruett, P]]
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[[Category: Pruett P]]
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[[Category: Structural genomic]]
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[[Category: Schormann N]]
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[[Category: Schormann, N]]
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[[Category: Symersky J]]
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[[Category: Symersky, J]]
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[[Category: Zhang Y]]
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[[Category: Zhang, Y]]
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[[Category: Bag-1 cochaperone]]
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[[Category: Chaperone]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Secsg]]
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Current revision

Structural Genomics of Caenorhabditis elegans: Structure of BAG-1 protein

PDB ID 1t7s

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